Gene detail

BW28_RS00485

Histidine kinase, Classic

Clostridioides difficile · GCF_001757605

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001757605#BW28_RS00485Stable P2CS identifier used across views.
GenomeGCF_001757605Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503671Run 6 · 37 sequences · id 100% · cov 80%
External referencesWP_022616668.1 · MIST4 BW28_RS00485RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BW28_RS00485
Domain-by-domain annotation2 items
1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw tokenHisKA:182:0.0000000000000186:240:59:64
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw tokenHATPase_c:293:2.76e-18:391:100:109
  • Raw architecture: HisKA:182:0.0000000000000186:240:59:64#HATPase_c:293:2.76e-18:391:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001757605::NZ_JFOF01000007.1::G00047
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span67136-68979Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW28_17950RefSeq proteinWP_022616668.1
Context group IDGCF_001757605::NZ_JFOF01000007.1::G00047
Context members
BW28_RS00480BW28_RS00485
Partner locus tags
BW28_RS00480BW28_RS00485
Partner old locus tags
BW28_17945BW28_17950
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022616668.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBW28_RS00485Primary locus identifier stored in the genes table.
Old locus tagBW28_17950Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOF01000007.1Sequence record reported by the local genomic context database.
Genomic interval67 798-68 979 nt1 182 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span67 136-68 979 ntGCF_001757605::NZ_JFOF01000007.1::G00047

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001757605::NZ_JFOF01000007.1::G00047

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOF01000007.1All displayed genes belong to this local TCS context.
Neighborhood span67 136-68 979 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
67 136 nt68 979 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BW28_RS00480GCF_001757605#BW28_RS00480
RROmpR

67 136-67 798 nt · Forward (+)

Old locus BW28_17945RefSeq WP_003426273.1
BW28_RS00485GCF_001757605#BW28_RS00485
HKClassicCurrent focus

67 798-68 979 nt · Forward (+)

Old locus BW28_17950RefSeq WP_022616668.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503671Run 6 · HK · 37 sequences
Representative sequenceGCF_000531625#BN168_RS02555Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503671

Simplified PFAM architecture for HKOC_2503671

PFAM domain coverage: 162 / 393 aa (41.2%)

1 aa393 aa
HisKA: 179-240 aaHisKAHATPase_c: 292-391 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[179-240] | HATPase_c[292-391]
  • Domain count: 2
  • Matched identifier: HKOC_2503671
  • Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Visualization

Representative gene: GCF_000531625#BN168_RS02555

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757605
AssemblyASM175760v1 · Contighaploid
Genome composition4 317 574 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key