1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw token
HisKA:124:0.00000135:189:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BW25_RS15780
Histidine kinase, Classic
Clostridioides difficile · GCF_001757585
ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001757585#BW25_RS15780Stable P2CS identifier used across views.
GenomeGCF_001757585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 343 aa (51.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa343 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
235-343 aa · 109 aa · 31.8% of protein
Raw token
HATPase_c:235:2.4e-27:343:109:109- Raw architecture: HisKA:124:0.00000135:189:66:64#HATPase_c:235:2.4e-27:343:109:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_001757585::NZ_JFOH01000051.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span234300-236011Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW25_15200RefSeq proteinWP_070117112.1
Context group ID
GCF_001757585::NZ_JFOH01000051.1::G00042Context members
BW25_RS15780BW25_RS15785
Partner locus tags
BW25_RS15780BW25_RS15785
Partner old locus tags
BW25_15200BW25_15205
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_070117112.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBW25_RS15780Primary locus identifier stored in the genes table.
Old locus tagBW25_15200Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOH01000051.1Sequence record reported by the local genomic context database.
Genomic interval234 300-235 331 nt1 032 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span234 300-236 011 ntGCF_001757585::NZ_JFOH01000051.1::G00042
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001757585::NZ_JFOH01000051.1::G00042Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOH01000051.1All displayed genes belong to this local TCS context.
Neighborhood span234 300-236 011 nt1 712 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
234 300 nt236 011 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
BW25_RS15780GCF_001757585#BW25_RS15780
HKClassicCurrent focus
234 300-235 331 nt · Reverse (-)
BW25_RS15785GCF_001757585#BW25_RS15785
RROmpR
235 328-236 011 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001757585#BW25_RS15780The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2828461
Simplified PFAM architecture for HKOC_2828461
PFAM domain coverage: 174 / 343 aa (50.7%)
1 aa343 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[124-189] | HATPase_c[235-342]
- Domain count: 2
- Matched identifier: HKOC_2828461
- Positioned domains: HisKA 124-189 ; HATPase_c 235-342
Cluster members and taxonomy
Representative gene: GCF_001757585#BW25_RS15780
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757585
AssemblyASM175758v1 · Contighaploid
Genome composition4 181 809 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key