1 HisKA#1
87-150 aa · 64 aa · 21.0% of protein
Raw token
HisKA:87:0.0000000587:150:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BW25_RS15220
Histidine kinase, Classic
Clostridioides difficile · GCF_001757585
ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001757585#BW25_RS15220Stable P2CS identifier used across views.
GenomeGCF_001757585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 305 aa (56.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
197-304 aa · 108 aa · 35.4% of protein
Raw token
HATPase_c:197:3.5e-27:304:108:109- Raw architecture: HisKA:87:0.0000000587:150:64:64#HATPase_c:197:3.5e-27:304:108:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_001757585::NZ_JFOH01000051.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span122404-124022Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW25_14640RefSeq proteinWP_042741670.1
Context group ID
GCF_001757585::NZ_JFOH01000051.1::G00041Context members
BW25_RS15215BW25_RS15220
Partner locus tags
BW25_RS15215BW25_RS15220
Partner old locus tags
BW25_14635BW25_14640
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_042741670.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N4TGG0Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N4TGG0_9FIRMDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBW25_RS15220Primary locus identifier stored in the genes table.
Old locus tagBW25_14640Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOH01000051.1Sequence record reported by the local genomic context database.
Genomic interval123 105-124 022 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span122 404-124 022 ntGCF_001757585::NZ_JFOH01000051.1::G00041
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001757585::NZ_JFOH01000051.1::G00041Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOH01000051.1All displayed genes belong to this local TCS context.
Neighborhood span122 404-124 022 nt1 619 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
122 404 nt124 022 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
BW25_RS15215GCF_001757585#BW25_RS15215
RROmpR
122 404-123 102 nt · Forward (+)
BW25_RS15220GCF_001757585#BW25_RS15220
HKClassicCurrent focus
123 105-124 022 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000828225#SE46_RS20695Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2882151
Simplified PFAM architecture for HKOC_2882151
PFAM domain coverage: 171 / 305 aa (56.1%)
1 aa305 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[87-150] | HATPase_c[197-303]
- Domain count: 2
- Matched identifier: HKOC_2882151
- Positioned domains: HisKA 87-150 ; HATPase_c 197-303
Cluster members and taxonomy
Representative gene: GCF_000828225#SE46_RS20695
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757585
AssemblyASM175758v1 · Contighaploid
Genome composition4 181 809 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key