Gene detail

BW25_RS08355

Histidine kinase, Classic

Clostridioides difficile · GCF_001757585

ClassHKTypeClassicLength689 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001757585#BW25_RS08355Stable P2CS identifier used across views.
GenomeGCF_001757585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0794312Run 6 · 23 sequences · id 100% · cov 80% · representative
External referencesWP_070117666.1 · MIST4 BW25_RS08355RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length689 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 689 aa (23.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa689 aa
HisKA: 460-527 aa (68 aa)1HATPase_c: 573-666 aa (94 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
460-527 aa · 68 aa · 9.9% of protein
Raw tokenHisKA:460:0.0000000000000205:527:68:64
2 HATPase_c#2
573-666 aa · 94 aa · 13.6% of protein
Raw tokenHATPase_c:573:0.00000000000089:666:98:109
  • Raw architecture: HisKA:460:0.0000000000000205:527:68:64#HATPase_c:573:0.00000000000089:666:98:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001757585::NZ_JFOH01000022.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span349153-352110Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW25_05580RefSeq proteinWP_070117666.1
Context group IDGCF_001757585::NZ_JFOH01000022.1::G00016
Context members
BW25_RS08355BW25_RS08365
Partner locus tags
BW25_RS08355BW25_RS08365
Partner old locus tags
BW25_05580BW25_05590
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_070117666.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBW25_RS08355Primary locus identifier stored in the genes table.
Old locus tagBW25_05580Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOH01000022.1Sequence record reported by the local genomic context database.
Genomic interval349 153-351 222 nt2 070 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span349 153-352 110 ntGCF_001757585::NZ_JFOH01000022.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001757585::NZ_JFOH01000022.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOH01000022.1All displayed genes belong to this local TCS context.
Neighborhood span349 153-352 110 nt2 958 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
349 153 nt352 110 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BW25_RS08355GCF_001757585#BW25_RS08355
HKClassicCurrent focus

349 153-351 222 nt · Reverse (-)

Old locus BW25_05580RefSeq WP_070117666.1
BW25_RS08365GCF_001757585#BW25_RS08365
RROmpR

351 418-352 110 nt · Reverse (-)

Old locus BW25_05590RefSeq WP_003430378.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0794312Run 6 · HK · 23 sequences
Representative sequenceGCF_001757585#BW25_RS08355The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0794312

Simplified PFAM architecture for HKOC_0794312

PFAM domain coverage: 160 / 689 aa (23.2%)

1 aa689 aa
HisKA: 460-527 aaHisKAHATPase_c: 574-665 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[460-527] | HATPase_c[574-665]
  • Domain count: 2
  • Matched identifier: HKOC_0794312
  • Positioned domains: HisKA 460-527 ; HATPase_c 574-665
Cluster members and taxonomy
Visualization

Representative gene: GCF_001757585#BW25_RS08355

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757585
AssemblyASM175758v1 · Contighaploid
Genome composition4 181 809 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key