1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000611:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BW25_RS04660
Histidine kinase, Classic
Clostridioides difficile · GCF_001757585
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_001757585#BW25_RS04660Stable P2CS identifier used across views.
GenomeGCF_001757585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:1e-28:668:104:109- Raw architecture: HisKA:449:0.00000000611:514:66:64#HATPase_c:565:1e-28:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpentadGCF_001757585::NZ_JFOH01000010.1::G00006
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span127684-133408Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW25_01790RefSeq proteinWP_021427717.1
Context group ID
GCF_001757585::NZ_JFOH01000010.1::G00006Context members
BW25_RS04645BW25_RS04650BW25_RS04655BW25_RS04660BW25_RS04665
Partner locus tags
BW25_RS04645BW25_RS04650BW25_RS04655BW25_RS04660BW25_RS04665
Partner old locus tags
BW25_01775BW25_01780BW25_01785BW25_01790BW25_01795
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021427717.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DA33Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DA33_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBW25_RS04660Primary locus identifier stored in the genes table.
Old locus tagBW25_01790Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOH01000010.1Sequence record reported by the local genomic context database.
Genomic interval130 644-132 659 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span127 684-133 408 ntGCF_001757585::NZ_JFOH01000010.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001757585::NZ_JFOH01000010.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOH01000010.1All displayed genes belong to this local TCS context.
Neighborhood span127 684-133 408 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
127 684 nt133 408 nt
Neighborhood gene cards
5 genes in the current local neighborhood.
BW25_RS04645GCF_001757585#BW25_RS04645
HKClassic
127 684-128 799 nt · Reverse (-)
BW25_RS04650GCF_001757585#BW25_RS04650
RROmpR
128 835-129 533 nt · Reverse (-)
BW25_RS04655GCF_001757585#BW25_RS04655
RROmpR
129 914-130 594 nt · Reverse (-)
BW25_RS04660GCF_001757585#BW25_RS04660
HKClassicCurrent focus
130 644-132 659 nt · Reverse (-)
BW25_RS04665GCF_001757585#BW25_RS04665
RROmpR
132 731-133 408 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS16915Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842488
Simplified PFAM architecture for HKOC_0842488
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842488
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS16915
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757585
AssemblyASM175758v1 · Contighaploid
Genome composition4 181 809 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key