Gene detail

DCP99_RS10180

Histidine kinase, Classic

Clostridioides difficile · GCF_001704805

ClassHKTypeClassicLength900 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001704805#DCP99_RS10180Stable P2CS identifier used across views.
GenomeGCF_001704805Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0405723Run 6 · 24 sequences · id 100% · cov 80%
External referencesWP_021375442.1 · MIST4 DCP99_RS10180RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length900 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage514 / 900 aa (57.1%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa900 aa
KdpD: 22-230 aa (209 aa)1GAF_3: 533-656 aa (124 aa)2HisKA: 676-743 aa (68 aa)3HATPase_c: 787-899 aa (113 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
22-230 aa · 209 aa · 23.2% of protein
Raw tokenKdpD:22:5.48e-134:230:209:210
2 GAF_3#2
533-656 aa · 124 aa · 13.8% of protein
Raw tokenGAF_3:533:0.00000418:656:129:129
3 HisKA#3
676-743 aa · 68 aa · 7.6% of protein
Raw tokenHisKA:676:0.00000000000547:743:68:64
4 HATPase_c#4
787-899 aa · 113 aa · 12.6% of protein
Raw tokenHATPase_c:787:1.7e-30:899:113:109
  • Raw architecture: KdpD:22:5.48e-134:230:209:210#GAF_3:533:0.00000418:656:129:129#HisKA:676:0.00000000000547:743:68:64#HATPase_c:787:1.7e-30:899:113:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001704805::NZ_MBGB02000013.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span39884-43318Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBCD45_RS10180RefSeq proteinWP_021375442.1
Context group IDGCF_001704805::NZ_MBGB02000013.1::G00005
Context members
DCP99_RS10180DCP99_RS10185
Partner locus tags
DCP99_RS10180DCP99_RS10185
Partner old locus tags
BCD45_RS10180BCD45_RS10185
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021375442.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDCP99_RS10180Primary locus identifier stored in the genes table.
Old locus tagBCD45_RS10180Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MBGB02000013.1Sequence record reported by the local genomic context database.
Genomic interval39 884-42 586 nt2 703 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span39 884-43 318 ntGCF_001704805::NZ_MBGB02000013.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001704805::NZ_MBGB02000013.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MBGB02000013.1All displayed genes belong to this local TCS context.
Neighborhood span39 884-43 318 nt3 435 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
39 884 nt43 318 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DCP99_RS10180GCF_001704805#DCP99_RS10180
HKClassicCurrent focus

39 884-42 586 nt · Forward (+)

Old locus BCD45_RS10180RefSeq WP_021375442.1
DCP99_RS10185GCF_001704805#DCP99_RS10185
RROmpR

42 620-43 318 nt · Forward (+)

Old locus BCD45_RS10185RefSeq WP_003428622.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0405723Run 6 · HK · 24 sequences
Representative sequenceGCF_000449185#QCW_RS09360Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0405723

Simplified PFAM architecture for HKOC_0405723

PFAM domain coverage: 494 / 900 aa (54.9%)

1 aa900 aa
KdpD: 22-230 aaKdpDDUF4118: 409-514 aaDUF4118HisKA: 676-743 aaHisKAHATPase_c: 788-898 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[22-230] | DUF4118[409-514] | HisKA[676-743] | HATPase_c[788-898]
  • Domain count: 4
  • Matched identifier: HKOC_0405723
  • Positioned domains: KdpD 22-230 ; DUF4118 409-514 ; HisKA 676-743 ; HATPase_c 788-898
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS09360

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 24 over 24 total members. Page 1 / 1.

GCF_000449185#QCW_RS09360 (representative)
QCW_RS09360 · HK · Classic
RefSeq: WP_021375442.1
GCF_001704755#DCQ03_RS10830
DCQ03_RS10830 · HK · Classic
RefSeq: WP_021375442.1
GCF_001704805#DCP99_RS10180
DCP99_RS10180 · HK · Classic
RefSeq: WP_021375442.1
GCF_002165155#DCQ05_RS12950
DCQ05_RS12950 · HK · Classic
RefSeq: WP_021375442.1
GCF_002250295#B7359_RS00855
B7359_RS00855 · HK · Classic
RefSeq: WP_021375442.1
GCF_004314505#E0O34_RS16865
E0O34_RS16865 · HK · Classic
RefSeq: WP_021375442.1
GCF_004314745#E0O51_RS13375
E0O51_RS13375 · HK · Classic
RefSeq: WP_021375442.1
GCF_005786645#EDC95_RS11240
EDC95_RS11240 · HK · Classic
RefSeq: WP_021375442.1
GCF_012029905#GSQ35_RS16650
GSQ35_RS16650 · HK · Classic
RefSeq: WP_021375442.1
GCF_012955915#HGQ81_RS03160
HGQ81_RS03160 · HK · Classic
RefSeq: WP_021375442.1
GCF_024260145#NMF85_RS15685
NMF85_RS15685 · HK · Classic
RefSeq: WP_021375442.1
GCF_024260265#NMF89_RS09210
NMF89_RS09210 · HK · Classic
RefSeq: WP_021375442.1
GCF_024260515#NMF45_RS11330
NMF45_RS11330 · HK · Classic
RefSeq: WP_021375442.1
GCF_024262205#NMG00_RS17310
NMG00_RS17310 · HK · Classic
RefSeq: WP_021375442.1
GCF_024262325#NMF88_RS09265
NMF88_RS09265 · HK · Classic
RefSeq: WP_021375442.1
GCF_024262365#NMF91_RS14425
NMF91_RS14425 · HK · Classic
RefSeq: WP_021375442.1
GCF_028597315#PSM44_RS00515
PSM44_RS00515 · HK · Classic
RefSeq: WP_021375442.1
GCF_036017135#VXE66_RS04025
VXE66_RS04025 · HK · Classic
RefSeq: WP_021375442.1
GCF_036861275#VH742_RS10350
VH742_RS10350 · HK · Classic
RefSeq: WP_021375442.1
GCF_038755145#ABCR36_RS05130
ABCR36_RS05130 · HK · Classic
RefSeq: WP_021375442.1
GCF_043107495#ACGAKC_RS06805
ACGAKC_RS06805 · HK · Classic
RefSeq: WP_021375442.1
GCF_900014225#A4020_RS07115
A4020_RS07115 · HK · Classic
RefSeq: WP_021375442.1
GCF_900096045#DK464_RS15530
DK464_RS15530 · HK · Classic
RefSeq: WP_021375442.1
GCF_900165975#B2A22_RS07820
B2A22_RS07820 · HK · Classic
RefSeq: WP_021375442.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001704805
AssemblyASM170480v2 · Contighaploid
Genome composition4 137 970 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 92 · HK 41 · RR 49CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key