Gene detail

DCQ03_RS13745

Histidine kinase, Classic

Clostridioides difficile · GCF_001704755

ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001704755#DCQ03_RS13745Stable P2CS identifier used across views.
GenomeGCF_001704755Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2440983Run 6 · 40 sequences · id 100% · cov 80%
External referencesWP_021376058.1 · MIST4 DCQ03_RS13745RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 400 aa (45.0%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa400 aa
His_kinase: 205-283 aa (79 aa)1HATPase_c: 300-400 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
205-283 aa · 79 aa · 19.8% of protein
Raw tokenHis_kinase:205:7.06e-31:283:80:80
2 HATPase_c#2
300-400 aa · 101 aa · 25.3% of protein
Raw tokenHATPase_c:300:0.00000000157:400:108:109
  • Raw architecture: His_kinase:205:7.06e-31:283:80:80#HATPase_c:300:0.00000000157:400:108:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001704755::NZ_MBMH02000327.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1658-3635Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBCD44_RS13735RefSeq proteinWP_021376058.1
Context group IDGCF_001704755::NZ_MBMH02000327.1::G00030
Context members
DCQ03_RS13740DCQ03_RS13745
Partner locus tags
DCQ03_RS13740DCQ03_RS13745
Partner old locus tags
BCD44_RS13730BCD44_RS13735
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021376058.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDCQ03_RS13745Primary locus identifier stored in the genes table.
Old locus tagBCD44_RS13735Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MBMH02000327.1Sequence record reported by the local genomic context database.
Genomic interval2 433-3 635 nt1 203 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 658-3 635 ntGCF_001704755::NZ_MBMH02000327.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001704755::NZ_MBMH02000327.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MBMH02000327.1All displayed genes belong to this local TCS context.
Neighborhood span1 658-3 635 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 658 nt3 635 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DCQ03_RS13740GCF_001704755#DCQ03_RS13740
RRLytTR

1 658-2 428 nt · Reverse (-)

Old locus BCD44_RS13730RefSeq WP_021376106.1
DCQ03_RS13745GCF_001704755#DCQ03_RS13745
HKClassicCurrent focus

2 433-3 635 nt · Reverse (-)

Old locus BCD44_RS13735RefSeq WP_021376058.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2440983Run 6 · HK · 40 sequences
Representative sequenceGCF_000449185#QCW_RS13155Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2440983

Simplified PFAM architecture for HKOC_2440983

PFAM domain coverage: 342 / 400 aa (85.5%)

1 aa400 aa
5TM-5TMR_LYT: 27-190 aa5TM-5TMR_LYTHis_kinase: 205-281 aaHis_kinaseHATPase_c: 299-399 aaHATPase_c
5TM-5TMR_LYTHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[27-190] | His_kinase[205-281] | HATPase_c[299-399]
  • Domain count: 3
  • Matched identifier: HKOC_2440983
  • Positioned domains: 5TM-5TMR_LYT 27-190 ; His_kinase 205-281 ; HATPase_c 299-399
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS13155

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001704755
AssemblyASM170475v2 · Contighaploid
Genome composition3 975 153 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 89 · HK 41 · RR 47CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key