Gene detail

AWN51_RS11725

Histidine kinase, Classic

Enterococcus faecium · GCF_001543555

ClassHKTypeClassicLength483 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001543555#AWN51_RS11725Stable P2CS identifier used across views.
GenomeGCF_001543555Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1594090Run 6 · 917 sequences · id 100% · cov 80%
External referencesWP_002295478.1 · A0AAV3L2G0 · MIST4 AWN51_RS11725RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length483 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 483 aa (50.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa483 aa
HAMP: 201-253 aa (53 aa)1His_kinase: 268-347 aa (80 aa)2HATPase_c: 363-474 aa (112 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
201-253 aa · 53 aa · 11.0% of protein
Raw tokenHAMP:201:0.0000126:253:53:69
2 His_kinase#2
268-347 aa · 80 aa · 16.6% of protein
Raw tokenHis_kinase:268:1.59e-27:347:80:80
3 HATPase_c#3
363-474 aa · 112 aa · 23.2% of protein
Raw tokenHATPase_c:363:2.9e-16:474:113:109
  • Raw architecture: HAMP:201:0.0000126:253:53:69#His_kinase:268:1.59e-27:347:80:80#HATPase_c:363:2.9e-16:474:113:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001543555::NZ_LRAS01000214.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span46631-49643Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAWN51_11760RefSeq proteinWP_002295478.1
Context group IDGCF_001543555::NZ_LRAS01000214.1::G00019
Context members
AWN51_RS11725AWN51_RS11730
Partner locus tags
AWN51_RS11725AWN51_RS11730
Partner old locus tags
AWN51_11760AWN51_11765
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002295478.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3L2G0Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3L2G0_ENTFCDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAWN51_RS11725Primary locus identifier stored in the genes table.
Old locus tagAWN51_11760Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LRAS01000214.1Sequence record reported by the local genomic context database.
Genomic interval46 631-48 082 nt1 452 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span46 631-49 643 ntGCF_001543555::NZ_LRAS01000214.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001543555::NZ_LRAS01000214.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LRAS01000214.1All displayed genes belong to this local TCS context.
Neighborhood span46 631-49 643 nt3 013 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
46 631 nt49 643 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

AWN51_RS11725GCF_001543555#AWN51_RS11725
HKClassicCurrent focus

46 631-48 082 nt · Forward (+)

Old locus AWN51_11760RefSeq WP_002295478.1
AWN51_RS11730GCF_001543555#AWN51_RS11730
RRunclassified

48 075-49 643 nt · Forward (+)

Old locus AWN51_11765RefSeq WP_002299000.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1594090Run 6 · HK · 917 sequences
Representative sequenceGCF_000172655#EFME1071_RS13680Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1594090

Simplified PFAM architecture for HKOC_1594090

PFAM domain coverage: 239 / 483 aa (49.5%)

1 aa483 aa
HAMP: 204-253 aaHAMPHis_kinase: 269-346 aaHis_kinaseHATPase_c: 363-473 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[204-253] | His_kinase[269-346] | HATPase_c[363-473]
  • Domain count: 3
  • Matched identifier: HKOC_1594090
  • Positioned domains: HAMP 204-253 ; His_kinase 269-346 ; HATPase_c 363-473
Cluster members and taxonomy
Visualization

Representative gene: GCF_000172655#EFME1071_RS13680

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 352 · GCF_001543555
AssemblyASM154355v1 · Scaffoldhaploid
Genome composition3 170 658 bp · 38,0% GCEnterococcus faecium
Signal transduction countsGenes 46 · HK 22 · RR 24CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key