Gene detail

M2E15_RS00140

Histidine kinase, Hybrid

Bacillus mycoides · GCF_001484805

ClassHKTypeHybridLength896 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_001484805#M2E15_RS00140Stable P2CS identifier used across views.
GenomeGCF_001484805Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_0412974Run 6 · 23 sequences · id 100% · cov 80%
External referencesWP_002186519.1 · A0AAP8H002 · MIST4 M2E15_RS00140RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

CHASE3HAMPGAFHisKAHATPase_cResponse_reg
Protein length896 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage634 / 896 aa (70.8%)Merged over positioned domains only.
Domain description1 CHASE3,1 HAMP,1 GAF,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa896 aa
CHASE3: 46-172 aa (127 aa)1HAMP: 184-254 aa (71 aa)2GAF: 274-410 aa (137 aa)3HisKA: 496-563 aa (68 aa)4HATPase_c: 610-731 aa (122 aa)5Response_reg: 778-886 aa (109 aa)6
Domain-by-domain annotation6 items
1 CHASE3#1
46-172 aa · 127 aa · 14.2% of protein
Raw tokenCHASE3:46:2.89e-17:172:135:138
2 HAMP#2
184-254 aa · 71 aa · 7.9% of protein
Raw tokenHAMP:184:0.000000391:254:71:69
3 GAF#3
274-410 aa · 137 aa · 15.3% of protein
Raw tokenGAF:274:0.00000467:410:140:133
4 HisKA#4
496-563 aa · 68 aa · 7.6% of protein
Raw tokenHisKA:496:4.19e-17:563:68:64
5 HATPase_c#5
610-731 aa · 122 aa · 13.6% of protein
Raw tokenHATPase_c:610:6.25e-31:731:122:109
6 Response_reg#6
778-886 aa · 109 aa · 12.2% of protein
Raw tokenResponse_reg:778:5.21e-31:886:109:111
  • Raw architecture: CHASE3:46:2.89e-17:172:135:138#HAMP:184:0.000000391:254:71:69#GAF:274:0.00000467:410:140:133#HisKA:496:4.19e-17:563:68:64#HATPase_c:610:6.25e-31:731:122:109#Response_reg:778:5.21e-31:886:109:111
  • Domain description: 1 CHASE3,1 HAMP,1 GAF,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_001484805::NZ_LLWA01000001.1::G00002
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span21832-24522Genomic interval covered by the local TCS group.
Identifiers
Old locus tagM2E15_0983RefSeq proteinWP_002186519.1
Context group IDGCF_001484805::NZ_LLWA01000001.1::G00002
Context members
M2E15_RS00140
Partner locus tags
M2E15_RS00140
Partner old locus tags
M2E15_0983
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002186519.1Primary protein accession used for annex mappings.
UniProt accessionA0AAP8H002Primary UniProt accession resolved in the annex database.
UniProt IDA0AAP8H002_BACMYDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagM2E15_RS00140Primary locus identifier stored in the genes table.
Old locus tagM2E15_0983Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LLWA01000001.1Sequence record reported by the local genomic context database.
Genomic interval21 832-24 522 nt2 691 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span21 832-24 522 ntGCF_001484805::NZ_LLWA01000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001484805::NZ_LLWA01000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LLWA01000001.1All displayed genes belong to this local TCS context.
Neighborhood span21 832-24 522 nt2 691 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
21 832 nt24 522 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

M2E15_RS00140GCF_001484805#M2E15_RS00140
HKHybridCurrent focus

21 832-24 522 nt · Forward (+)

Old locus M2E15_0983RefSeq WP_002186519.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0412974Run 6 · HK · 23 sequences
Representative sequenceGCF_000290695#IKM_RS21635Use this link to inspect the representative gene detail.
PFAM architectureCHASE3 + GAF_2 + HisKA + HATPase_c + Response_reg5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0412974

Simplified PFAM architecture for HKOC_0412974

PFAM domain coverage: 562 / 896 aa (62.7%)

1 aa896 aa
CHASE3: 45-172 aaCHASE3GAF_2: 278-411 aaGAF_2HisKA: 496-563 aaHisKAHATPase_c: 611-731 aaHATPase_cResponse_reg: 778-888 aaResponse_reg
CHASE3GAF_2HisKAHATPase_cResponse_reg
  • Simplified architecture: CHASE3 + GAF_2 + HisKA + HATPase_c + Response_reg
  • Raw architecture: CHASE3[45-172] | GAF_2[278-411] | HisKA[496-563] | HATPase_c[611-731] | Response_reg[778-888]
  • Domain count: 5
  • Matched identifier: HKOC_0412974
  • Positioned domains: CHASE3 45-172 ; GAF_2 278-411 ; HisKA 496-563 ; HATPase_c 611-731 ; Response_reg 778-888
Cluster members and taxonomy
Visualization

Representative gene: GCF_000290695#IKM_RS21635

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 405 · GCF_001484805
AssemblyM2E_15 · Scaffoldhaploid
Genome composition6 077 838 bp · 35,0% GCBacillus mycoides
Signal transduction countsGenes 135 · HK 72 · RR 62CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key