Gene detail

ARA08_RS11965

Histidine kinase, Classic

Eubacterium ramulus · GCF_001406295

ClassHKTypeClassicLength589 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001406295#ARA08_RS11965Stable P2CS identifier used across views.
GenomeGCF_001406295Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_1115312Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_055290689.1 · A0A173V1V5 · MIST4 ARA08_RS11965RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length589 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage253 / 589 aa (43.0%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa589 aa
HAMP: 298-367 aa (70 aa)1His_kinase: 382-461 aa (80 aa)2HATPase_c: 479-581 aa (103 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
298-367 aa · 70 aa · 11.9% of protein
Raw tokenHAMP:298:0.0000000191:367:70:69
2 His_kinase#2
382-461 aa · 80 aa · 13.6% of protein
Raw tokenHis_kinase:382:3.69e-28:461:80:80
3 HATPase_c#3
479-581 aa · 103 aa · 17.5% of protein
Raw tokenHATPase_c:479:1.55e-16:581:110:109
  • Raw architecture: HAMP:298:0.0000000191:367:70:69#His_kinase:382:3.69e-28:461:80:80#HATPase_c:479:1.55e-16:581:110:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001406295::NZ_CYYA01000020.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span16247-19541Genomic interval covered by the local TCS group.
Identifiers
Old locus tagERS852448_02447RefSeq proteinWP_055290689.1
Context group IDGCF_001406295::NZ_CYYA01000020.1::G00030
Context members
ARA08_RS11965ARA08_RS11970
Partner locus tags
ARA08_RS11965ARA08_RS11970
Partner old locus tags
ERS852448_02447ERS852448_02448
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055290689.1Primary protein accession used for annex mappings.
UniProt accessionA0A173V1V5Primary UniProt accession resolved in the annex database.
UniProt IDA0A173V1V5_EUBRADisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagARA08_RS11965Primary locus identifier stored in the genes table.
Old locus tagERS852448_02447Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CYYA01000020.1Sequence record reported by the local genomic context database.
Genomic interval16 247-18 016 nt1 770 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span16 247-19 541 ntGCF_001406295::NZ_CYYA01000020.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001406295::NZ_CYYA01000020.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CYYA01000020.1All displayed genes belong to this local TCS context.
Neighborhood span16 247-19 541 nt3 295 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
16 247 nt19 541 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ARA08_RS11965GCF_001406295#ARA08_RS11965
HKClassicCurrent focus

16 247-18 016 nt · Reverse (-)

Old locus ERS852448_02447RefSeq WP_055290689.1
ARA08_RS11970GCF_001406295#ARA08_RS11970
RRunclassified

17 994-19 541 nt · Reverse (-)

Old locus ERS852448_02448RefSeq WP_055290691.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1115312Run 6 · HK · 2 sequences
Representative sequenceGCF_001406295#ARA08_RS11965The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1115312

Simplified PFAM architecture for HKOC_1115312

PFAM domain coverage: 182 / 589 aa (30.9%)

1 aa589 aa
His_kinase: 382-461 aaHis_kinaseHATPase_c: 480-581 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[382-461] | HATPase_c[480-581]
  • Domain count: 2
  • Matched identifier: HKOC_1115312
  • Positioned domains: His_kinase 382-461 ; HATPase_c 480-581
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406295#ARA08_RS11965

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 490 · GCF_001406295
Assembly13414_6#75 · Scaffoldhaploid
Genome composition3 307 376 bp · 43,0% GCEubacterium ramulus
Signal transduction countsGenes 68 · HK 34 · RR 33CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key