Gene detail

ARA08_RS06295

Histidine kinase, Classic

Eubacterium ramulus · GCF_001406295

ClassHKTypeClassicLength582 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001406295#ARA08_RS06295Stable P2CS identifier used across views.
GenomeGCF_001406295Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_1152807Run 6 · 3 sequences · id 100% · cov 80% · representative
External referencesWP_022036081.1 · A0A173T4G1 · MIST4 ARA08_RS06295RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length582 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 582 aa (41.1%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa582 aa
HAMP: 286-358 aa (73 aa)1His_kinase: 375-452 aa (78 aa)2HATPase_c: 495-582 aa (88 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
286-358 aa · 73 aa · 12.5% of protein
Raw tokenHAMP:286:0.00000000239:358:73:69
2 His_kinase#2
375-452 aa · 78 aa · 13.4% of protein
Raw tokenHis_kinase:375:0.00000000000000404:452:78:80
3 HATPase_c#3
495-582 aa · 88 aa · 15.1% of protein
Raw tokenHATPase_c:495:0.00000000785:582:88:109
  • Raw architecture: HAMP:286:0.00000000239:358:73:69#His_kinase:375:0.00000000000000404:452:78:80#HATPase_c:495:0.00000000785:582:88:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001406295::NZ_CYYA01000007.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span67649-70410Genomic interval covered by the local TCS group.
Identifiers
Old locus tagERS852448_01287RefSeq proteinWP_022036081.1
Context group IDGCF_001406295::NZ_CYYA01000007.1::G00013
Context members
ARA08_RS06295ARA08_RS06300
Partner locus tags
ARA08_RS06295ARA08_RS06300
Partner old locus tags
ERS852448_01287ERS852448_01288
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022036081.1Primary protein accession used for annex mappings.
UniProt accessionA0A173T4G1Primary UniProt accession resolved in the annex database.
UniProt IDA0A173T4G1_EUBRADisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagARA08_RS06295Primary locus identifier stored in the genes table.
Old locus tagERS852448_01287Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CYYA01000007.1Sequence record reported by the local genomic context database.
Genomic interval67 649-69 397 nt1 749 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span67 649-70 410 ntGCF_001406295::NZ_CYYA01000007.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001406295::NZ_CYYA01000007.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CYYA01000007.1All displayed genes belong to this local TCS context.
Neighborhood span67 649-70 410 nt2 762 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
67 649 nt70 410 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ARA08_RS06295GCF_001406295#ARA08_RS06295
HKClassicCurrent focus

67 649-69 397 nt · Reverse (-)

Old locus ERS852448_01287RefSeq WP_022036081.1
ARA08_RS06300GCF_001406295#ARA08_RS06300
RRunclassified

69 394-70 410 nt · Reverse (-)

Old locus ERS852448_01288RefSeq WP_022036082.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1152807Run 6 · HK · 3 sequences
Representative sequenceGCF_001406295#ARA08_RS06295The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1152807

Simplified PFAM architecture for HKOC_1152807

PFAM domain coverage: 235 / 582 aa (40.4%)

1 aa582 aa
HAMP: 311-357 aaHAMPHis_kinase: 376-453 aaHis_kinaseHATPase_c: 472-581 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[311-357] | His_kinase[376-453] | HATPase_c[472-581]
  • Domain count: 3
  • Matched identifier: HKOC_1152807
  • Positioned domains: HAMP 311-357 ; His_kinase 376-453 ; HATPase_c 472-581
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406295#ARA08_RS06295

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 490 · GCF_001406295
Assembly13414_6#75 · Scaffoldhaploid
Genome composition3 307 376 bp · 43,0% GCEubacterium ramulus
Signal transduction countsGenes 68 · HK 34 · RR 33CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key