1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.0000000033:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
AWU78_RS03125
Histidine kinase, Classic
Clostridioides difficile · GCF_001263675
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_001263675#AWU78_RS03125Stable P2CS identifier used across views.
GenomeGCF_001263675Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:4.05e-30:668:104:109- Raw architecture: HisKA:449:0.0000000033:514:66:64#HATPase_c:565:4.05e-30:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labeltriadGCF_001263675::NZ_BBYD01000053.1::G00018
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span72084-75578Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_001263675::NZ_BBYD01000053.1::G00018Context members
AWU78_RS03120AWU78_RS03125AWU78_RS03130
Partner locus tags
AWU78_RS03120AWU78_RS03125AWU78_RS03130
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021434858.1Primary protein accession used for annex mappings.
UniProt accessionA0A069A2K3Primary UniProt accession resolved in the annex database.
UniProt IDA0A069A2K3_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagAWU78_RS03125Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BBYD01000053.1Sequence record reported by the local genomic context database.
Genomic interval72 833-74 848 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span72 084-75 578 ntGCF_001263675::NZ_BBYD01000053.1::G00018
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001263675::NZ_BBYD01000053.1::G00018Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BBYD01000053.1All displayed genes belong to this local TCS context.
Neighborhood span72 084-75 578 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
72 084 nt75 578 nt
Neighborhood gene cards
3 genes in the current local neighborhood.
AWU78_RS03120GCF_001263675#AWU78_RS03120
RROmpR
72 084-72 761 nt · Forward (+)
AWU78_RS03125GCF_001263675#AWU78_RS03125
HKClassicCurrent focus
72 833-74 848 nt · Forward (+)
AWU78_RS03130GCF_001263675#AWU78_RS03130
RROmpR
74 898-75 578 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448765#QC5_RS16420Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842595
Simplified PFAM architecture for HKOC_0842595
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842595
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000448765#QC5_RS16420
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_001263675
AssemblyASM126367v1 · Contighaploid
Genome composition4 037 225 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key