Gene detail

TU65_RS04500

Histidine kinase, Classic

Bacillus wiedmannii · GCF_001044745

ClassHKTypeClassicLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001044745#TU65_RS04500Stable P2CS identifier used across views.
GenomeGCF_001044745Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1105242Run 6 · 106 sequences · id 100% · cov 80%
External referencesWP_000964666.1 · A0A1C4BVE7 · MIST4 TU65_RS04500RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage348 / 591 aa (58.9%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
HAMP: 176-244 aa (69 aa)1PAS: 255-355 aa (101 aa)2HisKA: 364-431 aa (68 aa)3HATPase_c: 478-587 aa (110 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
176-244 aa · 69 aa · 11.7% of protein
Raw tokenHAMP:176:0.00000000000000804:244:69:69
2 PAS#2
255-355 aa · 101 aa · 17.1% of protein
Raw tokenPAS:255:0.00000741:355:113:113
3 HisKA#3
364-431 aa · 68 aa · 11.5% of protein
Raw tokenHisKA:364:3.68e-18:431:68:64
4 HATPase_c#4
478-587 aa · 110 aa · 18.6% of protein
Raw tokenHATPase_c:478:2.07e-34:587:110:109
  • Raw architecture: HAMP:176:0.00000000000000804:244:69:69#PAS:255:0.00000741:355:113:113#HisKA:364:3.68e-18:431:68:64#HATPase_c:478:2.07e-34:587:110:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001044745::NZ_LABO01000014.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span19910-22401Genomic interval covered by the local TCS group.
Identifiers
Old locus tagTU65_04500RefSeq proteinWP_000964666.1
Context group IDGCF_001044745::NZ_LABO01000014.1::G00018
Context members
TU65_RS04495TU65_RS04500
Partner locus tags
TU65_RS04495TU65_RS04500
Partner old locus tags
TU65_04495TU65_04500
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000964666.1Primary protein accession used for annex mappings.
UniProt accessionA0A1C4BVE7Primary UniProt accession resolved in the annex database.
UniProt IDA0A1C4BVE7_BACTUDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagTU65_RS04500Primary locus identifier stored in the genes table.
Old locus tagTU65_04500Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LABO01000014.1Sequence record reported by the local genomic context database.
Genomic interval20 626-22 401 nt1 776 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span19 910-22 401 ntGCF_001044745::NZ_LABO01000014.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001044745::NZ_LABO01000014.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LABO01000014.1All displayed genes belong to this local TCS context.
Neighborhood span19 910-22 401 nt2 492 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
19 910 nt22 401 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

TU65_RS04495GCF_001044745#TU65_RS04495
RROmpR

19 910-20 626 nt · Forward (+)

Old locus TU65_04495RefSeq WP_000426862.1
TU65_RS04500GCF_001044745#TU65_RS04500
HKClassicCurrent focus

20 626-22 401 nt · Forward (+)

Old locus TU65_04500RefSeq WP_000964666.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1105242Run 6 · HK · 106 sequences
Representative sequenceGCF_000291375#IEI_RS18175Use this link to inspect the representative gene detail.
PFAM architectureHisK_sensor + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1105242

Simplified PFAM architecture for HKOC_1105242

PFAM domain coverage: 357 / 591 aa (60.4%)

1 aa591 aa
HisK_sensor: 38-163 aaHisK_sensorHAMP: 193-244 aaHAMPHisKA: 364-431 aaHisKAHATPase_c: 478-588 aaHATPase_c
HisK_sensorHAMPHisKAHATPase_c
  • Simplified architecture: HisK_sensor + HAMP + HisKA + HATPase_c
  • Raw architecture: HisK_sensor[38-163] | HAMP[193-244] | HisKA[364-431] | HATPase_c[478-588]
  • Domain count: 4
  • Matched identifier: HKOC_1105242
  • Positioned domains: HisK_sensor 38-163 ; HAMP 193-244 ; HisKA 364-431 ; HATPase_c 478-588
Cluster members and taxonomy
Visualization

Representative gene: GCF_000291375#IEI_RS18175

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 890 302 · GCF_001044745
AssemblyASM104474v1 · Scaffoldhaploid
Genome composition5 414 722 bp · 35,5% GCBacillus wiedmannii
Signal transduction countsGenes 122 · HK 65 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key