1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000352:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SE46_RS00855
Histidine kinase, Classic
Clostridioides difficile · GCF_000828225
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_000828225#SE46_RS00855Stable P2CS identifier used across views.
GenomeGCF_000828225Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:3.88e-30:668:104:109- Raw architecture: HisKA:449:0.00000000352:514:66:64#HATPase_c:565:3.88e-30:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labeltriadGCF_000828225::NZ_JXBR01000001.1::G00003
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span178051-181545Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000828225::NZ_JXBR01000001.1::G00003Context members
SE46_RS00850SE46_RS00855SE46_RS00860
Partner locus tags
SE46_RS00850SE46_RS00855SE46_RS00860
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021406845.1Primary protein accession used for annex mappings.
UniProt accessionA0A381KK05Primary UniProt accession resolved in the annex database.
UniProt IDA0A381KK05_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSE46_RS00855Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JXBR01000001.1Sequence record reported by the local genomic context database.
Genomic interval178 800-180 815 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span178 051-181 545 ntGCF_000828225::NZ_JXBR01000001.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000828225::NZ_JXBR01000001.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JXBR01000001.1All displayed genes belong to this local TCS context.
Neighborhood span178 051-181 545 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
178 051 nt181 545 nt
Neighborhood gene cards
3 genes in the current local neighborhood.
SE46_RS00850GCF_000828225#SE46_RS00850
RROmpR
178 051-178 728 nt · Forward (+)
SE46_RS00855GCF_000828225#SE46_RS00855
HKClassicCurrent focus
178 800-180 815 nt · Forward (+)
SE46_RS00860GCF_000828225#SE46_RS00860
RROmpR
180 865-181 545 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS17370Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842424
Simplified PFAM architecture for HKOC_0842424
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842424
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS17370
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_000828225
AssemblyASM82822v1 · Scaffoldhaploid
Genome composition4 513 340 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key