1 Response_reg#1
9-120 aa · 112 aa · 35.1% of protein
Raw token
Response_reg:9:2.01e-28:120:112:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BN2378_RS11370
Response regulator, PleD family
Clostridioides difficile · GCF_000826625
ClassRRTypePleDLength319 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000826625#BN2378_RS11370Stable P2CS identifier used across views.
GenomeGCF_000826625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regGGDEF
Protein length319 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage267 / 319 aa (83.7%)Merged over positioned domains only.
Domain description1 Response_reg,1 GGDEFSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa319 aa
Domain-by-domain annotation2 items
2 GGDEF#2
153-307 aa · 155 aa · 48.6% of protein
Raw token
GGDEF:153:6.15e-48:307:158:160- Raw architecture: Response_reg:9:2.01e-28:120:112:111#GGDEF:153:6.15e-48:307:158:160
- Domain description: 1 Response_reg,1 GGDEF
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000826625::NZ_CDND01000001.1::G00035
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span2469131-2470090Genomic interval covered by the local TCS group.
Identifiers
Old locus tagUA13_RS11365RefSeq proteinWP_009892662.1
Context group ID
GCF_000826625::NZ_CDND01000001.1::G00035Context members
BN2378_RS11370
Partner locus tags
BN2378_RS11370
Partner old locus tags
UA13_RS11365
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009892662.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R736Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R736_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBN2378_RS11370Primary locus identifier stored in the genes table.
Old locus tagUA13_RS11365Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CDND01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 469 131-2 470 090 nt960 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 469 131-2 470 090 ntGCF_000826625::NZ_CDND01000001.1::G00035
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000826625::NZ_CDND01000001.1::G00035Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CDND01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 469 131-2 470 090 nt960 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 469 131 nt2 470 090 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
BN2378_RS11370GCF_000826625#BN2378_RS11370
RRPleDCurrent focus
2 469 131-2 470 090 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0202755Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + GGDEF2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0533501
Simplified PFAM architecture for RROC_0533501
PFAM domain coverage: 266 / 319 aa (83.4%)
1 aa319 aa
Response_regGGDEF
- Simplified architecture: Response_reg + GGDEF
- Raw architecture: Response_reg[9-120] | GGDEF[153-306]
- Domain count: 2
- Matched identifier: RROC_0533501
- Positioned domains: Response_reg 9-120 ; Response_reg 9-120 ; GGDEF 153-306 ; GGDEF 153-306
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0202755
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_000826625
AssemblyG46R2_Q2 · Contighaploid
Genome composition4 189 317 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key