1 HAMP#1
170-237 aa · 68 aa · 14.7% of protein
Raw token
HAMP:170:0.00000000000177:237:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BN2378_RS11250
Histidine kinase, Classic
Clostridioides difficile · GCF_000826625
ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000826625#BN2378_RS11250Stable P2CS identifier used across views.
GenomeGCF_000826625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 464 aa (45.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa464 aa
Domain-by-domain annotation3 items
2 HisKA#2
249-308 aa · 60 aa · 12.9% of protein
Raw token
HisKA:249:0.000000000472:308:61:643 HATPase_c#3
355-439 aa · 85 aa · 18.3% of protein
Raw token
HATPase_c:355:0.00000000000000871:439:88:109- Raw architecture: HAMP:170:0.00000000000177:237:68:69#HisKA:249:0.000000000472:308:61:64#HATPase_c:355:0.00000000000000871:439:88:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000826625::NZ_CDND01000001.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2434296-2436330Genomic interval covered by the local TCS group.
Identifiers
Old locus tagUA13_RS11245RefSeq proteinWP_009888322.1
Context group ID
GCF_000826625::NZ_CDND01000001.1::G00032Context members
BN2378_RS11245BN2378_RS11250
Partner locus tags
BN2378_RS11245BN2378_RS11250
Partner old locus tags
UA13_RS11240UA13_RS11245
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009888322.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MZ97Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MZ97_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBN2378_RS11250Primary locus identifier stored in the genes table.
Old locus tagUA13_RS11245Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CDND01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 434 936-2 436 330 nt1 395 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 434 296-2 436 330 ntGCF_000826625::NZ_CDND01000001.1::G00032
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000826625::NZ_CDND01000001.1::G00032Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CDND01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 434 296-2 436 330 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 434 296 nt2 436 330 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
BN2378_RS11245GCF_000826625#BN2378_RS11245
RROmpR
2 434 296-2 434 943 nt · Forward (+)
BN2378_RS11250GCF_000826625#BN2378_RS11250
HKClassicCurrent focus
2 434 936-2 436 330 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0202630Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1783624
Simplified PFAM architecture for HKOC_1783624
PFAM domain coverage: 145 / 464 aa (31.3%)
1 aa464 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[250-308] | HATPase_c[355-440]
- Domain count: 2
- Matched identifier: HKOC_1783624
- Positioned domains: HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0202630
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_000826625
AssemblyG46R2_Q2 · Contighaploid
Genome composition4 189 317 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key