Gene detail

P247_RS00345

Histidine kinase, Classic

Francisella tularensis subsp. tularensis str. SCHU S4 substr. NR-10492 · GCF_000629005

ClassHKTypeClassicLength893 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000629005#P247_RS00345Stable P2CS identifier used across views.
GenomeGCF_000629005Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Thiotrichales; Francisellaceae; Francisella
Selected clusterHKOC_0424007Run 6 · 47 sequences · id 100% · cov 80%
External referencesWP_003022719.1 · A0AAD3AVJ6 · MIST4 P247_RS00345RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDHisKAHATPase_c
Protein length893 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage388 / 893 aa (43.4%)Merged over positioned domains only.
Domain description1 KdpD,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa893 aa
KdpD: 21-230 aa (210 aa)1HisKA: 668-732 aa (65 aa)2HATPase_c: 777-889 aa (113 aa)3
Domain-by-domain annotation3 items
1 KdpD#1
21-230 aa · 210 aa · 23.5% of protein
Raw tokenKdpD:21:1.61e-117:230:210:210
2 HisKA#2
668-732 aa · 65 aa · 7.3% of protein
Raw tokenHisKA:668:0.000000000000516:732:65:64
3 HATPase_c#3
777-889 aa · 113 aa · 12.7% of protein
Raw tokenHATPase_c:777:3.43e-27:889:113:109
  • Raw architecture: KdpD:21:1.61e-117:230:210:210#HisKA:668:0.000000000000516:732:65:64#HATPase_c:777:3.43e-27:889:113:109
  • Domain description: 1 KdpD,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000629005::NZ_KK211929.1::G00004
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1822854-1825535Genomic interval covered by the local TCS group.
Identifiers
Old locus tagP247_04056RefSeq proteinWP_003022719.1
Context group IDGCF_000629005::NZ_KK211929.1::G00004
Context members
P247_RS00345
Partner locus tags
P247_RS00345
Partner old locus tags
P247_04056
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003022719.1Primary protein accession used for annex mappings.
UniProt accessionA0AAD3AVJ6Primary UniProt accession resolved in the annex database.
UniProt IDA0AAD3AVJ6_FRATTDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagP247_RS00345Primary locus identifier stored in the genes table.
Old locus tagP247_04056Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KK211929.1Sequence record reported by the local genomic context database.
Genomic interval1 822 854-1 825 535 nt2 682 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 822 854-1 825 535 ntGCF_000629005::NZ_KK211929.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000629005::NZ_KK211929.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KK211929.1All displayed genes belong to this local TCS context.
Neighborhood span1 822 854-1 825 535 nt2 682 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 822 854 nt1 825 535 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

P247_RS00345GCF_000629005#P247_RS00345
HKClassicCurrent focus

1 822 854-1 825 535 nt · Reverse (-)

Old locus P247_04056RefSeq WP_003022719.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0424007Run 6 · HK · 47 sequences
Representative sequenceGCF_000008985#FTT_RS09185Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0424007

Simplified PFAM architecture for HKOC_0424007

PFAM domain coverage: 488 / 893 aa (54.6%)

1 aa893 aa
KdpD: 21-230 aaKdpDDUF4118: 406-503 aaDUF4118HisKA: 666-732 aaHisKAHATPase_c: 777-889 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[21-230] | DUF4118[406-503] | HisKA[666-732] | HATPase_c[777-889]
  • Domain count: 4
  • Matched identifier: HKOC_0424007
  • Positioned domains: KdpD 21-230 ; DUF4118 406-503 ; HisKA 666-732 ; HATPase_c 777-889
Cluster members and taxonomy
Visualization

Representative gene: GCF_000008985#FTT_RS09185

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 341 657 · GCF_000629005
AssemblyFran_tula_Schu_S4_NR-10492_V1 · Scaffoldhaploid
Genome composition1 894 828 bp · 32,5% GCFrancisella tularensis subsp. tularensis str. SCHU S4 substr. NR-10492
Signal transduction countsGenes 5 · HK 2 · RR 3CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderThiotrichalesFamilyFrancisellaceaeGenusFrancisella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Thiotrichales6Francisellaceae7Francisella

Related genes

Preview from the same derived genome key