Gene detail

BN165_RS01780

Histidine kinase, Classic

Clostridioides difficile E1 · GCF_000582865

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000582865#BN165_RS01780Stable P2CS identifier used across views.
GenomeGCF_000582865Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557654Run 6 · 299 sequences · id 100% · cov 80%
External referencesWP_003417817.1 · D5Q091 · MIST4 BN165_RS01780RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BN165_RS01780
Domain-by-domain annotation3 items
1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw tokenHAMP:84:0.000000527:152:70:69
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw tokenHisKA:164:0.0000000445:217:54:64
3 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw tokenHATPase_c:278:1.65e-20:382:106:109
  • Raw architecture: HAMP:84:0.000000527:152:70:69#HisKA:164:0.0000000445:217:54:64#HATPase_c:278:1.65e-20:382:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000582865::NZ_HF927493.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span12075-13897Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN165_210013RefSeq proteinWP_003417817.1
Context group IDGCF_000582865::NZ_HF927493.1::G00003
Context members
BN165_RS01775BN165_RS01780
Partner locus tags
BN165_RS01775BN165_RS01780
Partner old locus tags
BN165_210012BN165_210013
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003417817.1Primary protein accession used for annex mappings.
UniProt accessionD5Q091Primary UniProt accession resolved in the annex database.
UniProt IDD5Q091_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBN165_RS01780Primary locus identifier stored in the genes table.
Old locus tagBN165_210013Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF927493.1Sequence record reported by the local genomic context database.
Genomic interval12 737-13 897 nt1 161 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span12 075-13 897 ntGCF_000582865::NZ_HF927493.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000582865::NZ_HF927493.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF927493.1All displayed genes belong to this local TCS context.
Neighborhood span12 075-13 897 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
12 075 nt13 897 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BN165_RS01775GCF_000582865#BN165_RS01775
RROmpR

12 075-12 749 nt · Forward (+)

Old locus BN165_210012RefSeq WP_003417819.1
BN165_RS01780GCF_000582865#BN165_RS01780
HKClassicCurrent focus

12 737-13 897 nt · Forward (+)

Old locus BN165_210013RefSeq WP_003417817.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557654Run 6 · HK · 299 sequences
Representative sequenceGCF_000155065#QAE_RS0202410Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557654

Simplified PFAM architecture for HKOC_2557654

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557654
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0202410

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 299 total members. Page 1 / 6.

GCF_000155065#QAE_RS0202410 (representative)
QAE_RS0202410 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_000164175#HMPREF0220_RS08780
HMPREF0220_RS08780 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_000164655#HMPREF0219_RS16680
HMPREF0219_RS16680 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_000210435#CDM120_RS03250
CDM120_RS03250 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_000499505#BN164_RS02115
BN164_RS02115 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_000582865#BN165_RS01780
BN165_RS01780 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_001050575#BN163_RS01820
BN163_RS01820 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_001972065#BER35_RS03400
BER35_RS03400 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_001972115#BER34_RS16240
BER34_RS16240 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_002301695#BGU20_RS05485
BGU20_RS05485 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_002302685#BGU93_RS14915
BGU93_RS14915 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_002303305#BGU53_RS09165
BGU53_RS09165 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_002303425#BGU60_RS15340
BGU60_RS15340 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_002352505#V439_RS11130
V439_RS11130 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_002412385#V438_RS05940
V438_RS05940 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_002946515#C4E25_RS02780
C4E25_RS02780 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_002946535#C4E42_RS16405
C4E42_RS16405 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_002946555#C4E26_RS02780
C4E26_RS02780 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_003482165#CDIF29020_RS03025
CDIF29020_RS03025 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_003482365#CDIF29747_RS02780
CDIF29747_RS02780 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_003697205#EBB60_RS03220
EBB60_RS03220 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_003697225#EBL90_RS03365
EBL90_RS03365 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_003697245#EBL91_RS02770
EBL91_RS02770 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_004318565#E0Q96_RS05430
E0Q96_RS05430 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_004318785#E0Q93_RS09970
E0Q93_RS09970 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_008579085#F6C11_RS03715
F6C11_RS03715 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_009362915#FTB24_RS16150
FTB24_RS16150 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_012952655#HCN89_RS02605
HCN89_RS02605 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_015351855#ITI91_RS03280
ITI91_RS03280 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_015352255#ITJ05_RS09595
ITJ05_RS09595 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_016766955#JMW53_RS11120
JMW53_RS11120 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_016766975#JMW50_RS17890
JMW50_RS17890 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_016766995#JMW52_RS17910
JMW52_RS17910 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_016767015#JMW49_RS05615
JMW49_RS05615 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_016767035#JMW55_RS02565
JMW55_RS02565 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_016767055#JMW51_RS17835
JMW51_RS17835 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_016767095#JMW48_RS12200
JMW48_RS12200 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_016767115#JMW47_RS08660
JMW47_RS08660 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_016767135#JMW46_RS12330
JMW46_RS12330 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_017592625#J5O10_RS02740
J5O10_RS02740 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_018603395#KK111_RS02995
KK111_RS02995 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_018603455#KK110_RS02990
KK110_RS02990 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_018603475#KK112_RS02990
KK112_RS02990 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_018884725#E1H40_RS02710
E1H40_RS02710 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_019427665#K1N48_RS17360
K1N48_RS17360 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_019427725#K1N54_RS09245
K1N54_RS09245 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_020297505#LA365_RS15585
LA365_RS15585 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_021283625#LWE91_RS09430
LWE91_RS09430 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_021283665#LWF03_RS08275
LWF03_RS08275 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091
GCF_021283685#LWE71_RS05080
LWE71_RS05080 · HK · Classic
RefSeq: WP_003417817.1
UniProt: D5Q091

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 225 722 · GCF_000582865
AssemblyE1 · Scaffoldhaploid
Genome composition3 945 725 bp · 29,0% GCClostridioides difficile E1
Signal transduction countsGenes 96 · HK 48 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key