Gene detail

BN176_RS08950

Histidine kinase, Classic

Clostridioides difficile E19 · GCF_000531785

ClassHKTypeClassicLength477 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000531785#BN176_RS08950Stable P2CS identifier used across views.
GenomeGCF_000531785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1645510Run 6 · 2636 sequences · id 100% · cov 80%
External referencesWP_003430278.1 · A0A0H3N3K5 · MIST4 BN176_RS08950RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length477 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 477 aa (50.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BN176_RS08950
Domain-by-domain annotation3 items
1 HAMP#1
177-246 aa · 70 aa · 14.7% of protein
Raw tokenHAMP:177:0.00000000000000602:246:70:69
2 HisKA#2
253-317 aa · 65 aa · 13.6% of protein
Raw tokenHisKA:253:1.02e-16:317:65:64
3 HATPase_c#3
365-470 aa · 106 aa · 22.2% of protein
Raw tokenHATPase_c:365:6.76e-28:470:107:109
  • Raw architecture: HAMP:177:0.00000000000000602:246:70:69#HisKA:253:1.02e-16:317:65:64#HATPase_c:365:6.76e-28:470:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000531785::NZ_HF930318.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3716-5850Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN176_1630005RefSeq proteinWP_003430278.1
Context group IDGCF_000531785::NZ_HF930318.1::G00031
Context members
BN176_RS08945BN176_RS08950
Partner locus tags
BN176_RS08945BN176_RS08950
Partner old locus tags
BN176_1630004BN176_1630005
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003430278.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N3K5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N3K5_CLODCDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBN176_RS08950Primary locus identifier stored in the genes table.
Old locus tagBN176_1630005Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF930318.1Sequence record reported by the local genomic context database.
Genomic interval4 417-5 850 nt1 434 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 716-5 850 ntGCF_000531785::NZ_HF930318.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000531785::NZ_HF930318.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF930318.1All displayed genes belong to this local TCS context.
Neighborhood span3 716-5 850 nt2 135 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 716 nt5 850 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BN176_RS08945GCF_000531785#BN176_RS08945
RROmpR

3 716-4 414 nt · Forward (+)

Old locus BN176_1630004RefSeq WP_009889742.1
BN176_RS08950GCF_000531785#BN176_RS08950
HKClassicCurrent focus

4 417-5 850 nt · Forward (+)

Old locus BN176_1630005RefSeq WP_003430278.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1645510Run 6 · HK · 2636 sequences
Representative sequenceGCF_000003215#QAC_RS0209215Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1645510

Simplified PFAM architecture for HKOC_1645510

PFAM domain coverage: 220 / 477 aa (46.1%)

1 aa477 aa
HAMP: 197-246 aaHAMPHisKA: 253-316 aaHisKAHATPase_c: 365-470 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[197-246] | HisKA[253-316] | HATPase_c[365-470]
  • Domain count: 3
  • Matched identifier: HKOC_1645510
  • Positioned domains: HAMP 197-246 ; HisKA 253-316 ; HATPase_c 365-470
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0209215

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 215 071 · GCF_000531785
AssemblyE19 · Scaffoldhaploid
Genome composition3 983 885 bp · 28,5% GCClostridioides difficile E19
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key