Gene detail

BN176_RS08145

Histidine kinase, Classic

Clostridioides difficile E19 · GCF_000531785

ClassHKTypeClassicLength360 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000531785#BN176_RS08145Stable P2CS identifier used across views.
GenomeGCF_000531785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2746944Run 6 · 785 sequences · id 100% · cov 80%
External referencesWP_012816161.1 · A0A0H3N707 · MIST4 BN176_RS08145RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length360 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 360 aa (44.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa360 aa
HisKA: 135-198 aa (64 aa)1HATPase_c: 248-344 aa (97 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
135-198 aa · 64 aa · 17.8% of protein
Raw tokenHisKA:135:0.000000000000365:198:64:64
2 HATPase_c#2
248-344 aa · 97 aa · 26.9% of protein
Raw tokenHATPase_c:248:2.05e-21:344:97:109
  • Raw architecture: HisKA:135:0.000000000000365:198:64:64#HATPase_c:248:2.05e-21:344:97:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000531785::NZ_HF930303.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3929-5762Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN176_1480004RefSeq proteinWP_012816161.1
Context group IDGCF_000531785::NZ_HF930303.1::G00027
Context members
BN176_RS08140BN176_RS08145
Partner locus tags
BN176_RS08140BN176_RS08145
Partner old locus tags
BN176_1480003BN176_1480004
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012816161.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N707Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N707_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBN176_RS08145Primary locus identifier stored in the genes table.
Old locus tagBN176_1480004Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF930303.1Sequence record reported by the local genomic context database.
Genomic interval4 680-5 762 nt1 083 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 929-5 762 ntGCF_000531785::NZ_HF930303.1::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000531785::NZ_HF930303.1::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF930303.1All displayed genes belong to this local TCS context.
Neighborhood span3 929-5 762 nt1 834 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 929 nt5 762 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BN176_RS08140GCF_000531785#BN176_RS08140
RROmpR

3 929-4 630 nt · Forward (+)

Old locus BN176_1480003RefSeq WP_009889529.1
BN176_RS08145GCF_000531785#BN176_RS08145
HKClassicCurrent focus

4 680-5 762 nt · Forward (+)

Old locus BN176_1480004RefSeq WP_012816161.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2746944Run 6 · HK · 785 sequences
Representative sequenceGCF_000003215#QAC_RS0208405Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2746944

Simplified PFAM architecture for HKOC_2746944

PFAM domain coverage: 161 / 360 aa (44.7%)

1 aa360 aa
HisKA: 136-198 aaHisKAHATPase_c: 248-345 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[136-198] | HATPase_c[248-345]
  • Domain count: 2
  • Matched identifier: HKOC_2746944
  • Positioned domains: HisKA 136-198 ; HATPase_c 248-345
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0208405

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 215 071 · GCF_000531785
AssemblyE19 · Scaffoldhaploid
Genome composition3 983 885 bp · 28,5% GCClostridioides difficile E19
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key