Gene detail

BN176_RS02620

Histidine kinase, Classic

Clostridioides difficile E19 · GCF_000531785

ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000531785#BN176_RS02620Stable P2CS identifier used across views.
GenomeGCF_000531785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1783624Run 6 · 384 sequences · id 100% · cov 80%
External referencesWP_009888322.1 · A0A0H3MZ97 · MIST4 BN176_RS02620RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 464 aa (45.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BN176_RS02620
Domain-by-domain annotation3 items
1 HAMP#1
170-237 aa · 68 aa · 14.7% of protein
Raw tokenHAMP:170:0.00000000000177:237:68:69
2 HisKA#2
249-308 aa · 60 aa · 12.9% of protein
Raw tokenHisKA:249:0.000000000472:308:61:64
3 HATPase_c#3
355-439 aa · 85 aa · 18.3% of protein
Raw tokenHATPase_c:355:0.00000000000000871:439:88:109
  • Raw architecture: HAMP:170:0.00000000000177:237:68:69#HisKA:249:0.000000000472:308:61:64#HATPase_c:355:0.00000000000000871:439:88:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000531785::NZ_HF930193.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span13826-15860Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN176_380015RefSeq proteinWP_009888322.1
Context group IDGCF_000531785::NZ_HF930193.1::G00008
Context members
BN176_RS02615BN176_RS02620
Partner locus tags
BN176_RS02615BN176_RS02620
Partner old locus tags
BN176_380014BN176_380015
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009888322.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MZ97Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MZ97_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBN176_RS02620Primary locus identifier stored in the genes table.
Old locus tagBN176_380015Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF930193.1Sequence record reported by the local genomic context database.
Genomic interval14 466-15 860 nt1 395 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span13 826-15 860 ntGCF_000531785::NZ_HF930193.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000531785::NZ_HF930193.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF930193.1All displayed genes belong to this local TCS context.
Neighborhood span13 826-15 860 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
13 826 nt15 860 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BN176_RS02615GCF_000531785#BN176_RS02615
RROmpR

13 826-14 473 nt · Forward (+)

Old locus BN176_380014RefSeq WP_022620030.1
BN176_RS02620GCF_000531785#BN176_RS02620
HKClassicCurrent focus

14 466-15 860 nt · Forward (+)

Old locus BN176_380015RefSeq WP_009888322.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1783624Run 6 · HK · 384 sequences
Representative sequenceGCF_000003215#QAC_RS0202630Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1783624

Simplified PFAM architecture for HKOC_1783624

PFAM domain coverage: 145 / 464 aa (31.3%)

1 aa464 aa
HisKA: 250-308 aaHisKAHATPase_c: 355-440 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[250-308] | HATPase_c[355-440]
  • Domain count: 2
  • Matched identifier: HKOC_1783624
  • Positioned domains: HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0202630

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 215 071 · GCF_000531785
AssemblyE19 · Scaffoldhaploid
Genome composition3 983 885 bp · 28,5% GCClostridioides difficile E19
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key