1 HAMP#1
76-153 aa · 78 aa · 20.1% of protein
Raw token
HAMP:76:0.00000000759:153:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BN176_RS02545
Histidine kinase, Classic
Clostridioides difficile E19 · GCF_000531785
ClassHKTypeClassicLength389 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000531785#BN176_RS02545Stable P2CS identifier used across views.
GenomeGCF_000531785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length389 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 389 aa (64.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA#2
165-230 aa · 66 aa · 17.0% of protein
Raw token
HisKA:165:0.00000000114:230:66:643 HATPase_c#3
280-386 aa · 107 aa · 27.5% of protein
Raw token
HATPase_c:280:8.62e-27:386:107:109- Raw architecture: HAMP:76:0.00000000759:153:78:69#HisKA:165:0.00000000114:230:66:64#HATPase_c:280:8.62e-27:386:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000531785::NZ_HF930192.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span9194-11329Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN176_370013RefSeq proteinWP_330367801.1
Context group ID
GCF_000531785::NZ_HF930192.1::G00006Context members
BN176_RS02540BN176_RS02545
Partner locus tags
BN176_RS02540BN176_RS02545
Partner old locus tags
BN176_370012BN176_370013
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_330367801.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBN176_RS02545Primary locus identifier stored in the genes table.
Old locus tagBN176_370013Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF930192.1Sequence record reported by the local genomic context database.
Genomic interval10 160-11 329 nt1 170 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span9 194-11 329 ntGCF_000531785::NZ_HF930192.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000531785::NZ_HF930192.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF930192.1All displayed genes belong to this local TCS context.
Neighborhood span9 194-11 329 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 194 nt11 329 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
BN176_RS02540GCF_000531785#BN176_RS02540
RROmpR
9 194-9 886 nt · Forward (+)
BN176_RS02545GCF_000531785#BN176_RS02545
HKClassicCurrent focus
10 160-11 329 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000531785#BN176_RS02545The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2535785
Simplified PFAM architecture for HKOC_2535785
PFAM domain coverage: 223 / 389 aa (57.3%)
1 aa389 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[103-153] | HisKA[166-230] | HATPase_c[280-386]
- Domain count: 3
- Matched identifier: HKOC_2535785
- Positioned domains: HAMP 103-153 ; HisKA 166-230 ; HATPase_c 280-386
Cluster members and taxonomy
Representative gene: GCF_000531785#BN176_RS02545
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 215 071 · GCF_000531785
AssemblyE19 · Scaffoldhaploid
Genome composition3 983 885 bp · 28,5% GCClostridioides difficile E19
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key