Gene detail

BN175_RS05365

Histidine kinase, Classic

Clostridioides difficile T23 · GCF_000530795

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000530795#BN175_RS05365Stable P2CS identifier used across views.
GenomeGCF_000530795Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1504523Run 6 · 22 sequences · id 100% · cov 80%
External referencesWP_021426183.1 · MIST4 BN175_RS05365RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 212-279 aa (68 aa)1HisKA: 289-347 aa (59 aa)2HATPase_c: 395-495 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw tokenHAMP:212:0.00000634:279:68:69
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw tokenHisKA:289:4.03e-17:347:59:64
3 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw tokenHATPase_c:395:1.08e-27:495:106:109
  • Raw architecture: HAMP:212:0.00000634:279:68:69#HisKA:289:4.03e-17:347:59:64#HATPase_c:395:1.08e-27:495:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000530795::NZ_HF924247.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span23263-25456Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN175_1020021RefSeq proteinWP_021426183.1
Context group IDGCF_000530795::NZ_HF924247.1::G00018
Context members
BN175_RS05360BN175_RS05365
Partner locus tags
BN175_RS05360BN175_RS05365
Partner old locus tags
BN175_1020020BN175_1020021
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021426183.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBN175_RS05365Primary locus identifier stored in the genes table.
Old locus tagBN175_1020021Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF924247.1Sequence record reported by the local genomic context database.
Genomic interval23 969-25 456 nt1 488 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span23 263-25 456 ntGCF_000530795::NZ_HF924247.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000530795::NZ_HF924247.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF924247.1All displayed genes belong to this local TCS context.
Neighborhood span23 263-25 456 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
23 263 nt25 456 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BN175_RS05360GCF_000530795#BN175_RS05360
RROmpR

23 263-23 967 nt · Forward (+)

Old locus BN175_1020020RefSeq WP_009888771.1
BN175_RS05365GCF_000530795#BN175_RS05365
HKClassicCurrent focus

23 969-25 456 nt · Forward (+)

Old locus BN175_1020021RefSeq WP_021426183.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504523Run 6 · HK · 22 sequences
Representative sequenceGCF_000450785#QO7_RS04720Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504523

Simplified PFAM architecture for HKOC_1504523

PFAM domain coverage: 161 / 495 aa (32.5%)

1 aa495 aa
HisKA: 287-347 aaHisKAHATPase_c: 395-494 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[287-347] | HATPase_c[395-494]
  • Domain count: 2
  • Matched identifier: HKOC_1504523
  • Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450785#QO7_RS04720

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 22 over 22 total members. Page 1 / 1.

GCF_000450785#QO7_RS04720 (representative)
QO7_RS04720 · HK · Classic
RefSeq: WP_021426183.1
GCF_000452005#QUI_RS13550
QUI_RS13550 · HK · Classic
RefSeq: WP_021426183.1
GCF_000530795#BN175_RS05365
BN175_RS05365 · HK · Classic
RefSeq: WP_021426183.1
GCF_001971865#BER27_RS05180
BER27_RS05180 · HK · Classic
RefSeq: WP_021426183.1
GCF_002301165#BGU11_RS16620
BGU11_RS16620 · HK · Classic
RefSeq: WP_021426183.1
GCF_002301465#BGU24_RS05430
BGU24_RS05430 · HK · Classic
RefSeq: WP_021426183.1
GCF_002301525#BGU28_RS13030
BGU28_RS13030 · HK · Classic
RefSeq: WP_021426183.1
GCF_002301615#BGU34_RS13650
BGU34_RS13650 · HK · Classic
RefSeq: WP_021426183.1
GCF_002301715#BGU39_RS08575
BGU39_RS08575 · HK · Classic
RefSeq: WP_021426183.1
GCF_002303105#BGV21_RS09830
BGV21_RS09830 · HK · Classic
RefSeq: WP_021426183.1
GCF_002891615#AMR88_RS13570
AMR88_RS13570 · HK · Classic
RefSeq: WP_021426183.1
GCF_002954305#AMR91_RS16030
AMR91_RS16030 · HK · Classic
RefSeq: WP_021426183.1
GCF_004315425#E0P58_RS14190
E0P58_RS14190 · HK · Classic
RefSeq: WP_021426183.1
GCF_004315685#E0P55_RS06000
E0P55_RS06000 · HK · Classic
RefSeq: WP_021426183.1
GCF_005502205#E5N70_RS14015
E5N70_RS14015 · HK · Classic
RefSeq: WP_021426183.1
GCF_015351915#ITI95_RS13250
ITI95_RS13250 · HK · Classic
RefSeq: WP_021426183.1
GCF_015352285#ITJ11_RS14045
ITJ11_RS14045 · HK · Classic
RefSeq: WP_021426183.1
GCF_018885045#E1H24_RS05280
E1H24_RS05280 · HK · Classic
RefSeq: WP_021426183.1
GCF_900012005#C4Q47_RS05190
C4Q47_RS05190 · HK · Classic
RefSeq: WP_021426183.1
GCF_900243125#DBQ03_RS02740
DBQ03_RS02740 · HK · Classic
RefSeq: WP_021426183.1
GCF_900243205#DBQ24_RS10705
DBQ24_RS10705 · HK · Classic
RefSeq: WP_021426183.1
GCF_901004935#FJF68_RS16105
FJF68_RS16105 · HK · Classic
RefSeq: WP_021426183.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 215 070 · GCF_000530795
AssemblyT23 · Scaffoldhaploid
Genome composition4 078 839 bp · 28,5% GCClostridioides difficile T23
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key