Gene detail

BN180_RS02255

Histidine kinase, Classic

Clostridioides difficile E14 · GCF_000530475

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000530475#BN180_RS02255Stable P2CS identifier used across views.
GenomeGCF_000530475Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557909Run 6 · 301 sequences · id 100% · cov 80%
External referencesWP_021364232.1 · A0A9X8RLC8 · MIST4 BN180_RS02255RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa386 aa
HAMP: 84-152 aa (69 aa)1HisKA: 164-217 aa (54 aa)2HATPase_c: 278-382 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw tokenHAMP:84:0.000000572:152:70:69
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw tokenHisKA:164:0.0000000519:217:54:64
3 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw tokenHATPase_c:278:9.75e-21:382:106:109
  • Raw architecture: HAMP:84:0.000000572:152:70:69#HisKA:164:0.0000000519:217:54:64#HATPase_c:278:9.75e-21:382:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000530475::NZ_HF923333.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4306-6128Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN180_280004RefSeq proteinWP_021364232.1
Context group IDGCF_000530475::NZ_HF923333.1::G00006
Context members
BN180_RS02255BN180_RS02260
Partner locus tags
BN180_RS02255BN180_RS02260
Partner old locus tags
BN180_280004BN180_280005
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021364232.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RLC8Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RLC8_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBN180_RS02255Primary locus identifier stored in the genes table.
Old locus tagBN180_280004Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF923333.1Sequence record reported by the local genomic context database.
Genomic interval4 306-5 466 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 306-6 128 ntGCF_000530475::NZ_HF923333.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000530475::NZ_HF923333.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF923333.1All displayed genes belong to this local TCS context.
Neighborhood span4 306-6 128 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 306 nt6 128 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BN180_RS02255GCF_000530475#BN180_RS02255
HKClassicCurrent focus

4 306-5 466 nt · Reverse (-)

Old locus BN180_280004RefSeq WP_021364232.1
BN180_RS02260GCF_000530475#BN180_RS02260
RROmpR

5 454-6 128 nt · Reverse (-)

Old locus BN180_280005RefSeq WP_021364234.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557909Run 6 · HK · 301 sequences
Representative sequenceGCF_000448745#QC1_RS03545Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557909

Simplified PFAM architecture for HKOC_2557909

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557909
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS03545

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 215 075 · GCF_000530475
AssemblyE14 · Scaffoldhaploid
Genome composition4 131 267 bp · 28,5% GCClostridioides difficile E14
Signal transduction countsGenes 96 · HK 45 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key