Gene detail

BN180_RS02235

Histidine kinase, Classic

Clostridioides difficile E14 · GCF_000530475

ClassHKTypeClassicLength389 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000530475#BN180_RS02235Stable P2CS identifier used across views.
GenomeGCF_000530475Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1674086Run 6 · 679 sequences · id 100% · cov 80%
External referencesWP_021360160.1 · MIST4 BN180_RS02235RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length389 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 389 aa (64.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa389 aa
HAMP: 76-153 aa (78 aa)1HisKA: 165-230 aa (66 aa)2HATPase_c: 280-386 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
76-153 aa · 78 aa · 20.1% of protein
Raw tokenHAMP:76:0.00000000858:153:78:69
2 HisKA#2
165-230 aa · 66 aa · 17.0% of protein
Raw tokenHisKA:165:0.00000000124:230:66:64
3 HATPase_c#3
280-386 aa · 107 aa · 27.5% of protein
Raw tokenHATPase_c:280:1.2e-26:386:107:109
  • Raw architecture: HAMP:76:0.00000000858:153:78:69#HisKA:165:0.00000000124:230:66:64#HATPase_c:280:1.2e-26:386:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000530475::NZ_HF923332.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span9184-11319Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN180_270015RefSeq proteinWP_021360160.1
Context group IDGCF_000530475::NZ_HF923332.1::G00005
Context members
BN180_RS02230BN180_RS02235
Partner locus tags
BN180_RS02230BN180_RS02235
Partner old locus tags
BN180_270014BN180_270015
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021360160.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBN180_RS02235Primary locus identifier stored in the genes table.
Old locus tagBN180_270015Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF923332.1Sequence record reported by the local genomic context database.
Genomic interval10 150-11 319 nt1 170 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span9 184-11 319 ntGCF_000530475::NZ_HF923332.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000530475::NZ_HF923332.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF923332.1All displayed genes belong to this local TCS context.
Neighborhood span9 184-11 319 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 184 nt11 319 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BN180_RS02230GCF_000530475#BN180_RS02230
RROmpR

9 184-9 876 nt · Forward (+)

Old locus BN180_270014RefSeq WP_003434748.1
BN180_RS02235GCF_000530475#BN180_RS02235
HKClassicCurrent focus

10 150-11 319 nt · Forward (+)

Old locus BN180_270015RefSeq WP_021360160.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674086Run 6 · HK · 679 sequences
Representative sequenceGCF_000009205#CD630_RS02960Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674086

Simplified PFAM architecture for HKOC_1674086

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1674086
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS02960

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 215 075 · GCF_000530475
AssemblyE14 · Scaffoldhaploid
Genome composition4 131 267 bp · 28,5% GCClostridioides difficile E14
Signal transduction countsGenes 96 · HK 45 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key