Gene detail

BN174_RS12695

Histidine kinase, Classic

Clostridioides difficile E15 · GCF_000530295

ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000530295#BN174_RS12695Stable P2CS identifier used across views.
GenomeGCF_000530295Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2440985Run 6 · 34 sequences · id 100% · cov 80%
External referencesWP_021397154.1 · MIST4 BN174_RS12695RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 400 aa (45.0%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa400 aa
His_kinase: 205-283 aa (79 aa)1HATPase_c: 300-400 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
205-283 aa · 79 aa · 19.8% of protein
Raw tokenHis_kinase:205:2.28e-31:283:80:80
2 HATPase_c#2
300-400 aa · 101 aa · 25.3% of protein
Raw tokenHATPase_c:300:0.00000000161:400:108:109
  • Raw architecture: His_kinase:205:2.28e-31:283:80:80#HATPase_c:300:0.00000000161:400:108:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000530295::NZ_HF933642.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span12575-14552Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN174_2160012RefSeq proteinWP_021397154.1
Context group IDGCF_000530295::NZ_HF933642.1::G00042
Context members
BN174_RS12690BN174_RS12695
Partner locus tags
BN174_RS12690BN174_RS12695
Partner old locus tags
BN174_2160011BN174_2160012
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021397154.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBN174_RS12695Primary locus identifier stored in the genes table.
Old locus tagBN174_2160012Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF933642.1Sequence record reported by the local genomic context database.
Genomic interval13 350-14 552 nt1 203 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span12 575-14 552 ntGCF_000530295::NZ_HF933642.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000530295::NZ_HF933642.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF933642.1All displayed genes belong to this local TCS context.
Neighborhood span12 575-14 552 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
12 575 nt14 552 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BN174_RS12690GCF_000530295#BN174_RS12690
RRLytTR

12 575-13 345 nt · Reverse (-)

Old locus BN174_2160011RefSeq WP_009890815.1
BN174_RS12695GCF_000530295#BN174_RS12695
HKClassicCurrent focus

13 350-14 552 nt · Reverse (-)

Old locus BN174_2160012RefSeq WP_021397154.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2440985Run 6 · HK · 34 sequences
Representative sequenceGCF_000450145#QK3_RS13390Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2440985

Simplified PFAM architecture for HKOC_2440985

PFAM domain coverage: 342 / 400 aa (85.5%)

1 aa400 aa
5TM-5TMR_LYT: 27-190 aa5TM-5TMR_LYTHis_kinase: 205-281 aaHis_kinaseHATPase_c: 299-399 aaHATPase_c
5TM-5TMR_LYTHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[27-190] | His_kinase[205-281] | HATPase_c[299-399]
  • Domain count: 3
  • Matched identifier: HKOC_2440985
  • Positioned domains: 5TM-5TMR_LYT 27-190 ; His_kinase 205-281 ; HATPase_c 299-399
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450145#QK3_RS13390

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 34 over 34 total members. Page 1 / 1.

GCF_000450145#QK3_RS13390 (representative)
QK3_RS13390 · HK · Classic
RefSeq: WP_021397154.1
GCF_000452005#QUI_RS05475
QUI_RS05475 · HK · Classic
RefSeq: WP_021397154.1
GCF_000530295#BN174_RS12695
BN174_RS12695 · HK · Classic
RefSeq: WP_021397154.1
GCF_000531255#BN173_RS12745
BN173_RS12745 · HK · Classic
RefSeq: WP_021397154.1
GCF_002300855#BGT96_RS07530
BGT96_RS07530 · HK · Classic
RefSeq: WP_021397154.1
GCF_002301165#BGU11_RS13185
BGU11_RS13185 · HK · Classic
RefSeq: WP_021397154.1
GCF_002301255#BGU15_RS15970
BGU15_RS15970 · HK · Classic
RefSeq: WP_021397154.1
GCF_002302755#BGV00_RS00005
BGV00_RS00005 · HK · Classic
RefSeq: WP_021397154.1
GCF_002891495#AMR93_RS13585
AMR93_RS13585 · HK · Classic
RefSeq: WP_021397154.1
GCF_002891605#AMR89_RS00300
AMR89_RS00300 · HK · Classic
RefSeq: WP_021397154.1
GCF_002891615#AMR88_RS16015
AMR88_RS16015 · HK · Classic
RefSeq: WP_021397154.1
GCF_002891625#AMR90_RS02585
AMR90_RS02585 · HK · Classic
RefSeq: WP_021397154.1
GCF_004317965#E0Q58_RS05975
E0Q58_RS05975 · HK · Classic
RefSeq: WP_021397154.1
GCF_009831175#GSM30_RS01500
GSM30_RS01500 · HK · Classic
RefSeq: WP_021397154.1
GCF_012276945#GSQ50_RS01575
GSQ50_RS01575 · HK · Classic
RefSeq: WP_021397154.1
GCF_012956705#HGQ82_RS13255
HGQ82_RS13255 · HK · Classic
RefSeq: WP_021397154.1
GCF_023656865#NBN67_RS13105
NBN67_RS13105 · HK · Classic
RefSeq: WP_021397154.1
GCF_023656875#NB460_RS13110
NB460_RS13110 · HK · Classic
RefSeq: WP_021397154.1
GCF_023656905#NB459_RS13185
NB459_RS13185 · HK · Classic
RefSeq: WP_021397154.1
GCF_024259965#NMF99_RS18085
NMF99_RS18085 · HK · Classic
RefSeq: WP_021397154.1
GCF_024260045#NMF97_RS10650
NMF97_RS10650 · HK · Classic
RefSeq: WP_021397154.1
GCF_024260055#NMG01_RS16515
NMG01_RS16515 · HK · Classic
RefSeq: WP_021397154.1
GCF_024260125#NMF90_RS01090
NMF90_RS01090 · HK · Classic
RefSeq: WP_021397154.1
GCF_024260155#NMF83_RS11975
NMF83_RS11975 · HK · Classic
RefSeq: WP_021397154.1
GCF_024260185#NMF94_RS01510
NMF94_RS01510 · HK · Classic
RefSeq: WP_021397154.1
GCF_036688825#LFB11_RS04915
LFB11_RS04915 · HK · Classic
RefSeq: WP_021397154.1
GCF_036699155#LFB10_RS02570
LFB10_RS02570 · HK · Classic
RefSeq: WP_021397154.1
GCF_900008785#A4X89_RS07825
A4X89_RS07825 · HK · Classic
RefSeq: WP_021397154.1
GCF_900243095#DBQ06_RS01755
DBQ06_RS01755 · HK · Classic
RefSeq: WP_021397154.1
GCF_900243175#DBQ21_RS04305
DBQ21_RS04305 · HK · Classic
RefSeq: WP_021397154.1
GCF_900243185#DBQ32_RS12155
DBQ32_RS12155 · HK · Classic
RefSeq: WP_021397154.1
GCF_900243205#DBQ24_RS03945
DBQ24_RS03945 · HK · Classic
RefSeq: WP_021397154.1
GCF_901004525#FJF30_RS08505
FJF30_RS08505 · HK · Classic
RefSeq: WP_021397154.1
GCF_932185835#QV674_RS00530
QV674_RS00530 · HK · Classic
RefSeq: WP_021397154.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 215 069 · GCF_000530295
AssemblyE15 · Scaffoldhaploid
Genome composition4 325 791 bp · 28,0% GCClostridioides difficile E15
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key