1 HAMP#1
156-223 aa · 68 aa · 14.8% of protein
Raw token
HAMP:156:0.000002:223:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BN174_RS03150
Histidine kinase, Classic
Clostridioides difficile E15 · GCF_000530295
ClassHKTypeClassicLength461 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000530295#BN174_RS03150Stable P2CS identifier used across views.
GenomeGCF_000530295Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length461 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 461 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa461 aa
Domain-by-domain annotation3 items
2 HisKA#2
235-297 aa · 63 aa · 13.7% of protein
Raw token
HisKA:235:0.00000000000395:297:63:643 HATPase_c#3
346-457 aa · 112 aa · 24.3% of protein
Raw token
HATPase_c:346:9.66e-22:457:112:109- Raw architecture: HAMP:156:0.000002:223:68:69#HisKA:235:0.00000000000395:297:63:64#HATPase_c:346:9.66e-22:457:112:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000530295::NZ_HF933494.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6544-8579Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN174_680011RefSeq proteinWP_022619413.1
Context group ID
GCF_000530295::NZ_HF933494.1::G00013Context members
BN174_RS03145BN174_RS03150
Partner locus tags
BN174_RS03145BN174_RS03150
Partner old locus tags
BN174_680010BN174_680011
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_022619413.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBN174_RS03150Primary locus identifier stored in the genes table.
Old locus tagBN174_680011Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF933494.1Sequence record reported by the local genomic context database.
Genomic interval7 194-8 579 nt1 386 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 544-8 579 ntGCF_000530295::NZ_HF933494.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000530295::NZ_HF933494.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF933494.1All displayed genes belong to this local TCS context.
Neighborhood span6 544-8 579 nt2 036 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 544 nt8 579 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
BN174_RS03145GCF_000530295#BN174_RS03145
RROmpR
6 544-7 203 nt · Forward (+)
BN174_RS03150GCF_000530295#BN174_RS03150
HKClassicCurrent focus
7 194-8 579 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000530295#BN174_RS03150The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1820958
Simplified PFAM architecture for HKOC_1820958
PFAM domain coverage: 173 / 461 aa (37.5%)
1 aa461 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[236-297] | HATPase_c[346-456]
- Domain count: 2
- Matched identifier: HKOC_1820958
- Positioned domains: HisKA 236-297 ; HATPase_c 346-456
Cluster members and taxonomy
Representative gene: GCF_000530295#BN174_RS03150
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 215 069 · GCF_000530295
AssemblyE15 · Scaffoldhaploid
Genome composition4 325 791 bp · 28,0% GCClostridioides difficile E15
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key