Gene detail

P004_RS02980

Histidine kinase, Classic

Enterococcus faecalis EnGen0404 · GCF_000519505

ClassHKTypeClassicLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000519505#P004_RS02980Stable P2CS identifier used across views.
GenomeGCF_000519505Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1105110Run 6 · 1153 sequences · id 100% · cov 80%
External referencesWP_002390658.1 · A0ABC9TMN7 · MIST4 P004_RS02980RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likePAS_4HisKAHATPase_c
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage395 / 591 aa (66.8%)Merged over positioned domains only.
Domain description1 sCache_like,1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
sCache_like: 36-155 aa (120 aa)1PAS_4: 256-361 aa (106 aa)2HisKA: 365-428 aa (64 aa)3HATPase_c: 484-588 aa (105 aa)4
Domain-by-domain annotation4 items
1 sCache_like#1
36-155 aa · 120 aa · 20.3% of protein
Raw tokensCache_like:36:0.000000000299:155:121:114
2 PAS_4#2
256-361 aa · 106 aa · 17.9% of protein
Raw tokenPAS_4:256:0.00000000291:361:111:110
3 HisKA#3
365-428 aa · 64 aa · 10.8% of protein
Raw tokenHisKA:365:4.71e-16:428:64:64
4 HATPase_c#4
484-588 aa · 105 aa · 17.8% of protein
Raw tokenHATPase_c:484:1.15e-31:588:105:109
  • Raw architecture: sCache_like:36:0.000000000299:155:121:114#PAS_4:256:0.00000000291:361:111:110#HisKA:365:4.71e-16:428:64:64#HATPase_c:484:1.15e-31:588:105:109
  • Domain description: 1 sCache_like,1 PAS_4,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000519505::NZ_KI912966.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span599232-601714Genomic interval covered by the local TCS group.
Identifiers
Old locus tagP004_00586RefSeq proteinWP_002390658.1
Context group IDGCF_000519505::NZ_KI912966.1::G00005
Context members
P004_RS02975P004_RS02980
Partner locus tags
P004_RS02975P004_RS02980
Partner old locus tags
P004_00585P004_00586
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002390658.1Primary protein accession used for annex mappings.
UniProt accessionA0ABC9TMN7Primary UniProt accession resolved in the annex database.
UniProt IDA0ABC9TMN7_ENTFLDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagP004_RS02980Primary locus identifier stored in the genes table.
Old locus tagP004_00586Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI912966.1Sequence record reported by the local genomic context database.
Genomic interval599 939-601 714 nt1 776 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span599 232-601 714 ntGCF_000519505::NZ_KI912966.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000519505::NZ_KI912966.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI912966.1All displayed genes belong to this local TCS context.
Neighborhood span599 232-601 714 nt2 483 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
599 232 nt601 714 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

P004_RS02975GCF_000519505#P004_RS02975
RROmpR

599 232-599 942 nt · Forward (+)

Old locus P004_00585RefSeq WP_002360193.1
P004_RS02980GCF_000519505#P004_RS02980
HKClassicCurrent focus

599 939-601 714 nt · Forward (+)

Old locus P004_00586RefSeq WP_002390658.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1105110Run 6 · HK · 1153 sequences
Representative sequenceGCF_000147535#HMPREF9501_RS05705Use this link to inspect the representative gene detail.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1105110

Simplified PFAM architecture for HKOC_1105110

PFAM domain coverage: 276 / 591 aa (46.7%)

1 aa591 aa
PAS_4: 256-360 aaPAS_4HisKA: 366-429 aaHisKAHATPase_c: 481-587 aaHATPase_c
PAS_4HisKAHATPase_c
  • Simplified architecture: PAS_4 + HisKA + HATPase_c
  • Raw architecture: PAS_4[256-360] | HisKA[366-429] | HATPase_c[481-587]
  • Domain count: 3
  • Matched identifier: HKOC_1105110
  • Positioned domains: PAS_4 256-360 ; HisKA 366-429 ; HATPase_c 481-587
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147535#HMPREF9501_RS05705

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 391 474 · GCF_000519505
AssemblyEnte_faec_B292_V1 · Scaffoldhaploid
Genome composition3 150 800 bp · 37,5% GCEnterococcus faecalis EnGen0404
Signal transduction countsGenes 31 · HK 14 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key