Gene detail

HMPREF1547_RS12395

Histidine kinase, Classic

Blautia sp. KLE 1732 · GCF_000466565

ClassHKTypeClassicLength451 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000466565#HMPREF1547_RS12395Stable P2CS identifier used across views.
GenomeGCF_000466565Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1950224Run 6 · 9 sequences · id 100% · cov 80% · representative
External referencesWP_021652264.1 · A0ABW9X263 · MIST4 HMPREF1547_RS12395RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHisKAHATPase_c
Protein length451 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage281 / 451 aa (62.3%)Merged over positioned domains only.
Domain description1 sCache_like,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa451 aa
sCache_like: 31-135 aa (105 aa)1HisKA: 226-290 aa (65 aa)2HATPase_c: 335-445 aa (111 aa)3
Domain-by-domain annotation3 items
1 sCache_like#1
31-135 aa · 105 aa · 23.3% of protein
Raw tokensCache_like:31:0.0000000444:135:111:114
2 HisKA#2
226-290 aa · 65 aa · 14.4% of protein
Raw tokenHisKA:226:3.2e-16:290:65:64
3 HATPase_c#3
335-445 aa · 111 aa · 24.6% of protein
Raw tokenHATPase_c:335:1.52e-26:445:111:109
  • Raw architecture: sCache_like:31:0.0000000444:135:111:114#HisKA:226:3.2e-16:290:65:64#HATPase_c:335:1.52e-26:445:111:109
  • Domain description: 1 sCache_like,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000466565::NZ_KE993394.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span14840-16866Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1547_01158RefSeq proteinWP_021652264.1
Context group IDGCF_000466565::NZ_KE993394.1::G00035
Context members
HMPREF1547_RS12390HMPREF1547_RS12395
Partner locus tags
HMPREF1547_RS12390HMPREF1547_RS12395
Partner old locus tags
HMPREF1547_01157HMPREF1547_01158
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021652264.1Primary protein accession used for annex mappings.
UniProt accessionA0ABW9X263Primary UniProt accession resolved in the annex database.
UniProt IDA0ABW9X263_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 1Unique GO terms and literature references available below.
GO terms
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1547_RS12395Primary locus identifier stored in the genes table.
Old locus tagHMPREF1547_01158Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE993394.1Sequence record reported by the local genomic context database.
Genomic interval15 511-16 866 nt1 356 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span14 840-16 866 ntGCF_000466565::NZ_KE993394.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000466565::NZ_KE993394.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE993394.1All displayed genes belong to this local TCS context.
Neighborhood span14 840-16 866 nt2 027 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
14 840 nt16 866 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1547_RS12390GCF_000466565#HMPREF1547_RS12390
RROmpR

14 840-15 514 nt · Forward (+)

Old locus HMPREF1547_01157RefSeq WP_044961949.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1950224Run 6 · HK · 9 sequences
Representative sequenceGCF_000466565#HMPREF1547_RS12395The current gene is the representative for this cluster.
PFAM architecturesCache_like + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1950224

Simplified PFAM architecture for HKOC_1950224

PFAM domain coverage: 247 / 451 aa (54.8%)

1 aa451 aa
sCache_like: 59-131 aasCache_likeHisKA: 226-290 aaHisKAHATPase_c: 338-446 aaHATPase_c
sCache_likeHisKAHATPase_c
  • Simplified architecture: sCache_like + HisKA + HATPase_c
  • Raw architecture: sCache_like[59-131] | HisKA[226-290] | HATPase_c[338-446]
  • Domain count: 3
  • Matched identifier: HKOC_1950224
  • Positioned domains: sCache_like 59-131 ; HisKA 226-290 ; HATPase_c 338-446
Cluster members and taxonomy
Visualization

Representative gene: GCF_000466565#HMPREF1547_RS12395

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 226 324 · GCF_000466565
AssemblyASM46656v1 · Scaffoldhaploid
Genome composition3 573 774 bp · 44,0% GCBlautia sp. KLE 1732
Signal transduction countsGenes 80 · HK 39 · RR 41CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key