Gene detail

HMPREF1587_RS02575

Histidine kinase, Classic

Bifidobacterium breve JCP7499 · GCF_000466545

ClassHKTypeClassicLength429 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000466545#HMPREF1587_RS02575Stable P2CS identifier used across views.
GenomeGCF_000466545Bacteria; Bacillati; Actinomycetota; Actinomycetes; Bifidobacteriales; Bifidobacteriaceae; Bifidobacterium
Selected clusterHKOC_2180287Run 6 · 87 sequences · id 100% · cov 80%
External referencesWP_014483693.1 · A0A2U2RQD7 · MIST4 HMPREF1587_RS02575RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length429 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage147 / 429 aa (34.3%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF1587_RS02575
Domain-by-domain annotation2 items
1 HisKA_3#1
210-271 aa · 62 aa · 14.5% of protein
Raw tokenHisKA_3:210:0.00000000000111:271:65:68
2 HATPase_c#2
330-414 aa · 85 aa · 19.8% of protein
Raw tokenHATPase_c:330:0.000000000408:414:98:109
  • Raw architecture: HisKA_3:210:0.00000000000111:271:65:68#HATPase_c:330:0.000000000408:414:98:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000466545::NZ_KE993250.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span7671-9636Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1587_00935RefSeq proteinWP_014483693.1
Context group IDGCF_000466545::NZ_KE993250.1::G00015
Context members
HMPREF1587_RS02580HMPREF1587_RS02575
Partner locus tags
HMPREF1587_RS02580HMPREF1587_RS02575
Partner old locus tags
HMPREF1587_00934HMPREF1587_00935
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_014483693.1Primary protein accession used for annex mappings.
UniProt accessionA0A2U2RQD7Primary UniProt accession resolved in the annex database.
UniProt IDA0A2U2RQD7_BIFLNDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1587_RS02575Primary locus identifier stored in the genes table.
Old locus tagHMPREF1587_00935Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE993250.1Sequence record reported by the local genomic context database.
Genomic interval8 347-9 636 nt1 290 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span7 671-9 636 ntGCF_000466545::NZ_KE993250.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000466545::NZ_KE993250.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE993250.1All displayed genes belong to this local TCS context.
Neighborhood span7 671-9 636 nt1 966 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 671 nt9 636 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1587_RS02580GCF_000466545#HMPREF1587_RS02580
RRNarL

7 671-8 354 nt · Reverse (-)

Old locus HMPREF1587_00934RefSeq WP_003829522.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2180287Run 6 · HK · 87 sequences
Representative sequenceGCF_000158015#BIFBRE_RS04005Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2180287

Simplified PFAM architecture for HKOC_2180287

PFAM domain coverage: 155 / 429 aa (36.1%)

1 aa429 aa
HisKA_3: 213-274 aaHisKA_3HATPase_c: 324-416 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[213-274] | HATPase_c[324-416]
  • Domain count: 2
  • Matched identifier: HKOC_2180287
  • Positioned domains: HisKA_3 213-274 ; HATPase_c 324-416
Cluster members and taxonomy
Visualization

Representative gene: GCF_000158015#BIFBRE_RS04005

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 261 072 · GCF_000466545
AssemblyASM46654v1 · Scaffoldhaploid
Genome composition2 369 717 bp · 58,5% GCBifidobacterium breve JCP7499
Signal transduction countsGenes 26 · HK 9 · RR 15CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumActinomycetotaClassActinomycetesOrderBifidobacterialesFamilyBifidobacteriaceaeGenusBifidobacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Actinomycetota4Actinomycetes5Bifidobacteriales6Bifidobacteriaceae7Bifidobacterium

Related genes

Preview from the same derived genome key