1 HAMP#1
187-256 aa · 70 aa · 14.8% of protein
Raw token
HAMP:187:0.000000000000353:256:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CLOSYM_RS00565
Histidine kinase, Classic
[Clostridium] symbiosum ATCC 14940 · GCF_000466485
ClassHKTypeClassicLength473 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000466485#CLOSYM_RS00565Stable P2CS identifier used across views.
GenomeGCF_000466485Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length473 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 473 aa (49.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa473 aa
Domain-by-domain annotation3 items
2 HisKA#2
263-323 aa · 61 aa · 12.9% of protein
Raw token
HisKA:263:0.0000000000000628:323:61:643 HATPase_c#3
368-471 aa · 104 aa · 22.0% of protein
Raw token
HATPase_c:368:2.16e-22:471:108:109- Raw architecture: HAMP:187:0.000000000000353:256:70:69#HisKA:263:0.0000000000000628:323:61:64#HATPase_c:368:2.16e-22:471:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000466485::NZ_KE992793.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6013-8147Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCLOSYM_03285RefSeq proteinWP_021640540.1
Context group ID
GCF_000466485::NZ_KE992793.1::G00002Context members
CLOSYM_RS00560CLOSYM_RS00565
Partner locus tags
CLOSYM_RS00560CLOSYM_RS00565
Partner old locus tags
CLOSYM_03284CLOSYM_03285
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021640540.1Primary protein accession used for annex mappings.
UniProt accessionA0ABC9TV24Primary UniProt accession resolved in the annex database.
UniProt IDA0ABC9TV24_CLOSYDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCLOSYM_RS00565Primary locus identifier stored in the genes table.
Old locus tagCLOSYM_03285Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992793.1Sequence record reported by the local genomic context database.
Genomic interval6 726-8 147 nt1 422 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 013-8 147 ntGCF_000466485::NZ_KE992793.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000466485::NZ_KE992793.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992793.1All displayed genes belong to this local TCS context.
Neighborhood span6 013-8 147 nt2 135 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 013 nt8 147 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CLOSYM_RS00560GCF_000466485#CLOSYM_RS00560
RROmpR
6 013-6 729 nt · Forward (+)
CLOSYM_RS00565GCF_000466485#CLOSYM_RS00565
HKClassicCurrent focus
6 726-8 147 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000466485#CLOSYM_RS00565The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1687321
Simplified PFAM architecture for HKOC_1687321
PFAM domain coverage: 216 / 473 aa (45.7%)
1 aa473 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[205-255] | HisKA[262-323] | HATPase_c[370-472]
- Domain count: 3
- Matched identifier: HKOC_1687321
- Positioned domains: HAMP 205-255 ; HisKA 262-323 ; HATPase_c 370-472
Cluster members and taxonomy
Representative gene: GCF_000466485#CLOSYM_RS00565
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 411 472 · GCF_000466485
AssemblyASM46648v1 · Scaffoldhaploid
Genome composition4 823 675 bp · 47,5% GC[Clostridium] symbiosum ATCC 14940
Signal transduction countsGenes 113 · HK 55 · RR 55CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key