Gene detail

C677_RS14600

Histidine kinase, Classic

Clostridioides difficile F601 · GCF_000452345

ClassHKTypeClassicLength257 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000452345#C677_RS14600Stable P2CS identifier used across views.
GenomeGCF_000452345Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2916039Run 6 · 1358 sequences · id 100% · cov 80%
External referencesWP_021388531.1 · MIST4 C677_RS14600RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length257 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage157 / 257 aa (61.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa257 aa
HisKA: 46-93 aa (48 aa)1HATPase_c: 139-247 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
46-93 aa · 48 aa · 18.7% of protein
Raw tokenHisKA:46:0.000000692:93:53:64
2 HATPase_c#2
139-247 aa · 109 aa · 42.4% of protein
Raw tokenHATPase_c:139:5.01e-23:247:109:109
  • Raw architecture: HisKA:46:0.000000692:93:53:64#HATPase_c:139:5.01e-23:247:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000452345::NZ_AVNH01000029.1::G00048
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span140480-142186Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC677_2959RefSeq proteinWP_021388531.1
Context group IDGCF_000452345::NZ_AVNH01000029.1::G00048
Context members
C677_RS14600C677_RS14605
Partner locus tags
C677_RS14600C677_RS14605
Partner old locus tags
C677_2959C677_2960
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021388531.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC677_RS14600Primary locus identifier stored in the genes table.
Old locus tagC677_2959Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVNH01000029.1Sequence record reported by the local genomic context database.
Genomic interval140 480-141 253 nt774 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span140 480-142 186 ntGCF_000452345::NZ_AVNH01000029.1::G00048

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000452345::NZ_AVNH01000029.1::G00048

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVNH01000029.1All displayed genes belong to this local TCS context.
Neighborhood span140 480-142 186 nt1 707 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
140 480 nt142 186 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C677_RS14600GCF_000452345#C677_RS14600
HKClassicCurrent focus

140 480-141 253 nt · Reverse (-)

Old locus C677_2959RefSeq WP_021388531.1
C677_RS14605GCF_000452345#C677_RS14605
RROmpR

141 494-142 186 nt · Reverse (-)

Old locus C677_2960RefSeq WP_003429090.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2916039Run 6 · HK · 1358 sequences
Representative sequenceGCF_000154625#QAB_RS0217105Use this link to inspect the representative gene detail.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2916039

Simplified PFAM architecture for HKOC_2916039

PFAM domain coverage: 109 / 257 aa (42.4%)

1 aa257 aa
HATPase_c: 140-248 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[140-248]
  • Domain count: 1
  • Matched identifier: HKOC_2916039
  • Positioned domains: HATPase_c 140-248
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0217105

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 232 196 · GCF_000452345
AssemblyASM45234v2 · Contighaploid
Genome composition4 103 199 bp · 28,5% GCClostridioides difficile F601
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key