Gene detail

QUK_RS16140

Histidine kinase, Classic

Clostridioides difficile P61 · GCF_000452025

ClassHKTypeClassicLength376 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000452025#QUK_RS16140Stable P2CS identifier used across views.
GenomeGCF_000452025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2641403Run 6 · 590 sequences · id 100% · cov 80%
External referencesWP_011861876.1 · Q17ZU6 · MIST4 QUK_RS16140RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length376 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 376 aa (65.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QUK_RS16140
Domain-by-domain annotation3 items
1 HAMP#1
62-131 aa · 70 aa · 18.6% of protein
Raw tokenHAMP:62:0.0000000000108:131:70:69
2 HisKA#2
156-221 aa · 66 aa · 17.6% of protein
Raw tokenHisKA:156:0.00000000000000358:221:66:64
3 HATPase_c#3
267-376 aa · 110 aa · 29.3% of protein
Raw tokenHATPase_c:267:7.66e-18:376:111:109
  • Raw architecture: HAMP:62:0.0000000000108:131:70:69#HisKA:156:0.00000000000000358:221:66:64#HATPase_c:267:7.66e-18:376:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000452025::NZ_AVMR01000045.1::G00051
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span28278-30076Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQUK_3207RefSeq proteinWP_011861876.1
Context group IDGCF_000452025::NZ_AVMR01000045.1::G00051
Context members
QUK_RS16140QUK_RS16145
Partner locus tags
QUK_RS16140QUK_RS16145
Partner old locus tags
QUK_3207QUK_3208
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_011861876.1Primary protein accession used for annex mappings.
UniProt accessionQ17ZU6Primary UniProt accession resolved in the annex database.
UniProt IDQ17ZU6_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQUK_RS16140Primary locus identifier stored in the genes table.
Old locus tagQUK_3207Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVMR01000045.1Sequence record reported by the local genomic context database.
Genomic interval28 278-29 408 nt1 131 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span28 278-30 076 ntGCF_000452025::NZ_AVMR01000045.1::G00051

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000452025::NZ_AVMR01000045.1::G00051

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVMR01000045.1All displayed genes belong to this local TCS context.
Neighborhood span28 278-30 076 nt1 799 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
28 278 nt30 076 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QUK_RS16140GCF_000452025#QUK_RS16140
HKClassicCurrent focus

28 278-29 408 nt · Reverse (-)

Old locus QUK_3207RefSeq WP_011861876.1
QUK_RS16145GCF_000452025#QUK_RS16145
RROmpR

29 405-30 076 nt · Reverse (-)

Old locus QUK_3208RefSeq WP_016728515.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2641403Run 6 · HK · 590 sequences
Representative sequenceGCF_000009205#CD630_RS17045Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2641403

Simplified PFAM architecture for HKOC_2641403

PFAM domain coverage: 227 / 376 aa (60.4%)

1 aa376 aa
HAMP: 79-131 aaHAMPHisKA: 156-221 aaHisKAHATPase_c: 268-375 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[79-131] | HisKA[156-221] | HATPase_c[268-375]
  • Domain count: 3
  • Matched identifier: HKOC_2641403
  • Positioned domains: HAMP 79-131 ; HisKA 156-221 ; HATPase_c 268-375
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS17045

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 429 · GCF_000452025
AssemblyASM45202v2 · Contighaploid
Genome composition4 032 946 bp · 28,5% GCClostridioides difficile P61
Signal transduction countsGenes 100 · HK 49 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key