1 HisKA#1
207-272 aa · 66 aa · 15.3% of protein
Raw token
HisKA:207:0.000000000000035:272:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QUK_RS00110
Histidine kinase, Classic
Clostridioides difficile P61 · GCF_000452025
ClassHKTypeClassicLength430 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000452025#QUK_RS00110Stable P2CS identifier used across views.
GenomeGCF_000452025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length430 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 430 aa (41.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa430 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
320-430 aa · 111 aa · 25.8% of protein
Raw token
HATPase_c:320:1.3e-27:430:111:109- Raw architecture: HisKA:207:0.000000000000035:272:66:64#HATPase_c:320:1.3e-27:430:111:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000452025::NZ_AVMR01000004.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5450-7422Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQUK_3695RefSeq proteinWP_021364213.1
Context group ID
GCF_000452025::NZ_AVMR01000004.1::G00001Context members
QUK_RS00105QUK_RS00110
Partner locus tags
QUK_RS00105QUK_RS00110
Partner old locus tags
QUK_3694QUK_3695
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021364213.1Primary protein accession used for annex mappings.
UniProt accessionA0A7G9GSI8Primary UniProt accession resolved in the annex database.
UniProt IDA0A7G9GSI8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQUK_RS00110Primary locus identifier stored in the genes table.
Old locus tagQUK_3695Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVMR01000004.1Sequence record reported by the local genomic context database.
Genomic interval6 130-7 422 nt1 293 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 450-7 422 ntGCF_000452025::NZ_AVMR01000004.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000452025::NZ_AVMR01000004.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVMR01000004.1All displayed genes belong to this local TCS context.
Neighborhood span5 450-7 422 nt1 973 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 450 nt7 422 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QUK_RS00105GCF_000452025#QUK_RS00105
RROmpR
5 450-6 136 nt · Forward (+)
QUK_RS00110GCF_000452025#QUK_RS00110
HKClassicCurrent focus
6 130-7 422 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448745#QC1_RS03045Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2172345
Simplified PFAM architecture for HKOC_2172345
PFAM domain coverage: 174 / 430 aa (40.5%)
1 aa430 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[208-272] | HATPase_c[321-429]
- Domain count: 2
- Matched identifier: HKOC_2172345
- Positioned domains: HisKA 208-272 ; HATPase_c 321-429
Cluster members and taxonomy
Representative gene: GCF_000448745#QC1_RS03045
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 429 · GCF_000452025
AssemblyASM45202v2 · Contighaploid
Genome composition4 032 946 bp · 28,5% GCClostridioides difficile P61
Signal transduction countsGenes 100 · HK 49 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key