Gene detail

QUI_RS0119355

Histidine kinase, Classic

Clostridioides difficile P59 · GCF_000452005

ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000452005#QUI_RS0119355Stable P2CS identifier used across views.
GenomeGCF_000452005Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1355680Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_032519324.1 · MIST4 QUI_RS0119355RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QUI_RS0119355
Domain-by-domain annotation2 items
1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw tokenHisKA:309:0.0000000000000147:375:67:64
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw tokenHATPase_c:428:0.0000000402:513:90:109
  • Raw architecture: HisKA:309:0.0000000000000147:375:67:64#HATPase_c:428:0.0000000402:513:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000452005::NZ_AVMQ01000040.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5920-8197Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQUI_2469RefSeq proteinWP_032519324.1
Context group IDGCF_000452005::NZ_AVMQ01000040.1::G00037
Context members
QUI_RS07225QUI_RS0119355
Partner locus tags
QUI_RS07225QUI_RS0119355
Partner old locus tags
QUI_2467QUI_2469
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_032519324.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQUI_RS0119355Primary locus identifier stored in the genes table.
Old locus tagQUI_2469Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVMQ01000040.1Sequence record reported by the local genomic context database.
Genomic interval6 605-8 197 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 920-8 197 ntGCF_000452005::NZ_AVMQ01000040.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000452005::NZ_AVMQ01000040.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVMQ01000040.1All displayed genes belong to this local TCS context.
Neighborhood span5 920-8 197 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 920 nt8 197 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QUI_RS07225GCF_000452005#QUI_RS07225
RROmpR

5 920-6 636 nt · Forward (+)

Old locus QUI_2467RefSeq WP_009890517.1
QUI_RS0119355GCF_000452005#QUI_RS0119355
HKClassicCurrent focus

6 605-8 197 nt · Forward (+)

Old locus QUI_2469RefSeq WP_032519324.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1355680Run 6 · HK · 5 sequences
Representative sequenceGCF_000452005#QUI_RS0119355The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1355680

Simplified PFAM architecture for HKOC_1355680

PFAM domain coverage: 191 / 530 aa (36.0%)

1 aa530 aa
HAMP: 255-295 aaHAMPHisKA: 310-375 aaHisKAHATPase_c: 427-510 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-510]
  • Domain count: 3
  • Matched identifier: HKOC_1355680
  • Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-510
Cluster members and taxonomy
Visualization

Representative gene: GCF_000452005#QUI_RS0119355

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 428 · GCF_000452005
AssemblyASM45200v1 · Contighaploid
Genome composition4 223 549 bp · 28,5% GCClostridioides difficile P59
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key