Gene detail

QUC_RS06975

Histidine kinase, Classic

Clostridioides difficile P50 · GCF_000451965

ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000451965#QUC_RS06975Stable P2CS identifier used across views.
GenomeGCF_000451965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550381Run 6 · 61 sequences · id 100% · cov 80%
External referencesWP_021360467.1 · MIST4 QUC_RS06975RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa387 aa
HisKA_3: 188-253 aa (66 aa)1HATPase_c: 294-378 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw tokenHisKA_3:188:7.05e-20:253:67:68
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:294:0.000000000196:378:104:109
  • Raw architecture: HisKA_3:188:7.05e-20:253:67:68#HATPase_c:294:0.000000000196:378:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000451965::NZ_AVMO01000018.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span238829-240632Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQUC_1422RefSeq proteinWP_021360467.1
Context group IDGCF_000451965::NZ_AVMO01000018.1::G00018
Context members
QUC_RS06970QUC_RS06975
Partner locus tags
QUC_RS06970QUC_RS06975
Partner old locus tags
QUC_1421QUC_1422
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021360467.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQUC_RS06975Primary locus identifier stored in the genes table.
Old locus tagQUC_1422Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVMO01000018.1Sequence record reported by the local genomic context database.
Genomic interval239 469-240 632 nt1 164 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span238 829-240 632 ntGCF_000451965::NZ_AVMO01000018.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000451965::NZ_AVMO01000018.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVMO01000018.1All displayed genes belong to this local TCS context.
Neighborhood span238 829-240 632 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
238 829 nt240 632 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QUC_RS06970GCF_000451965#QUC_RS06970
RRNarL

238 829-239 476 nt · Reverse (-)

Old locus QUC_1421RefSeq WP_009896181.1
QUC_RS06975GCF_000451965#QUC_RS06975
HKClassicCurrent focus

239 469-240 632 nt · Reverse (-)

Old locus QUC_1422RefSeq WP_021360467.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550381Run 6 · HK · 61 sequences
Representative sequenceGCF_000448845#QAQ_RS06320Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550381

Simplified PFAM architecture for HKOC_2550381

PFAM domain coverage: 150 / 387 aa (38.8%)

1 aa387 aa
HisKA_3: 188-252 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550381
  • Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448845#QAQ_RS06320

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 425 · GCF_000451965
AssemblyASM45196v2 · Contighaploid
Genome composition4 395 649 bp · 28,5% GCClostridioides difficile P50
Signal transduction countsGenes 95 · HK 46 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key