Gene detail

QU5_RS03255

Histidine kinase, Classic

Clostridioides difficile P45 · GCF_000451885

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000451885#QU5_RS03255Stable P2CS identifier used across views.
GenomeGCF_000451885Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2881984Run 6 · 346 sequences · id 100% · cov 80%
External referencesWP_009892713.1 · A0A0H3N0D4 · MIST4 QU5_RS03255RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 305 aa (57.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
HisKA: 85-154 aa (70 aa)1HATPase_c: 201-304 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
85-154 aa · 70 aa · 23.0% of protein
Raw tokenHisKA:85:0.000000000000941:154:70:64
2 HATPase_c#2
201-304 aa · 104 aa · 34.1% of protein
Raw tokenHATPase_c:201:8.37e-28:304:106:109
  • Raw architecture: HisKA:85:0.000000000000941:154:70:64#HATPase_c:201:8.37e-28:304:106:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000451885::NZ_AVMK01000018.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span38876-40482Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQU5_0652RefSeq proteinWP_009892713.1
Context group IDGCF_000451885::NZ_AVMK01000018.1::G00013
Context members
QU5_RS03250QU5_RS03255
Partner locus tags
QU5_RS03250QU5_RS03255
Partner old locus tags
QU5_0651QU5_0652
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009892713.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N0D4Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N0D4_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQU5_RS03255Primary locus identifier stored in the genes table.
Old locus tagQU5_0652Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVMK01000018.1Sequence record reported by the local genomic context database.
Genomic interval39 565-40 482 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span38 876-40 482 ntGCF_000451885::NZ_AVMK01000018.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000451885::NZ_AVMK01000018.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVMK01000018.1All displayed genes belong to this local TCS context.
Neighborhood span38 876-40 482 nt1 607 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
38 876 nt40 482 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QU5_RS03250GCF_000451885#QU5_RS03250
RROmpR

38 876-39 565 nt · Forward (+)

Old locus QU5_0651RefSeq WP_009888424.1
QU5_RS03255GCF_000451885#QU5_RS03255
HKClassicCurrent focus

39 565-40 482 nt · Forward (+)

Old locus QU5_0652RefSeq WP_009892713.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2881984Run 6 · HK · 346 sequences
Representative sequenceGCF_000003215#QAC_RS0203320Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2881984

Simplified PFAM architecture for HKOC_2881984

PFAM domain coverage: 171 / 305 aa (56.1%)

1 aa305 aa
HisKA: 88-154 aaHisKAHATPase_c: 201-304 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[88-154] | HATPase_c[201-304]
  • Domain count: 2
  • Matched identifier: HKOC_2881984
  • Positioned domains: HisKA 88-154 ; HATPase_c 201-304
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0203320

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 421 · GCF_000451885
AssemblyASM45188v2 · Contighaploid
Genome composition4 097 352 bp · 28,5% GCClostridioides difficile P45
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key