Gene detail

QSO_RS04735

Histidine kinase, Classic

Clostridioides difficile P31 · GCF_000451785

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000451785#QSO_RS04735Stable P2CS identifier used across views.
GenomeGCF_000451785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1504245Run 6 · 349 sequences · id 100% · cov 80%
External referencesWP_009888772.1 · A0A0H3N1C9 · MIST4 QSO_RS04735RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 212-279 aa (68 aa)1HisKA: 289-347 aa (59 aa)2HATPase_c: 395-495 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw tokenHAMP:212:0.0000061:279:68:69
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw tokenHisKA:289:3.62e-17:347:59:64
3 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw tokenHATPase_c:395:2.74e-27:495:106:109
  • Raw architecture: HAMP:212:0.0000061:279:68:69#HisKA:289:3.62e-17:347:59:64#HATPase_c:395:2.74e-27:495:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000451785::NZ_AVMF01000025.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span52151-54344Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQSO_0971RefSeq proteinWP_009888772.1
Context group IDGCF_000451785::NZ_AVMF01000025.1::G00017
Context members
QSO_RS04730QSO_RS04735
Partner locus tags
QSO_RS04730QSO_RS04735
Partner old locus tags
QSO_0970QSO_0971
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009888772.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N1C9Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N1C9_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQSO_RS04735Primary locus identifier stored in the genes table.
Old locus tagQSO_0971Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVMF01000025.1Sequence record reported by the local genomic context database.
Genomic interval52 857-54 344 nt1 488 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span52 151-54 344 ntGCF_000451785::NZ_AVMF01000025.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000451785::NZ_AVMF01000025.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVMF01000025.1All displayed genes belong to this local TCS context.
Neighborhood span52 151-54 344 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
52 151 nt54 344 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QSO_RS04730GCF_000451785#QSO_RS04730
RROmpR

52 151-52 855 nt · Forward (+)

Old locus QSO_0970RefSeq WP_009888771.1
QSO_RS04735GCF_000451785#QSO_RS04735
HKClassicCurrent focus

52 857-54 344 nt · Forward (+)

Old locus QSO_0971RefSeq WP_009888772.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504245Run 6 · HK · 349 sequences
Representative sequenceGCF_000003215#QAC_RS0204900Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504245

Simplified PFAM architecture for HKOC_1504245

PFAM domain coverage: 161 / 495 aa (32.5%)

1 aa495 aa
HisKA: 287-347 aaHisKAHATPase_c: 395-494 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[287-347] | HATPase_c[395-494]
  • Domain count: 2
  • Matched identifier: HKOC_1504245
  • Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0204900

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 349 total members. Page 1 / 7.

GCF_000003215#QAC_RS0204900 (representative)
QAC_RS0204900 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000027105#CDR20291_RS04920
CDR20291_RS04920 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000085225#CD196_RS05050
CD196_RS05050 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000154645#UAA_RS0206770
UAA_RS0206770 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000154665#QAD_RS0205105
QAD_RS0205105 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000154685#AEC_RS0206370
AEC_RS0206370 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000155045#EAA_RS0204820
EAA_RS0204820 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000210455#CD7855_RS04910
CD7855_RS04910 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000211235#CDBI1_RS05000
CDBI1_RS05000 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000450145#QK3_RS05540
QK3_RS05540 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000450765#QO5_RS05725
QO5_RS05725 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000451065#QSC_RS04745
QSC_RS04745 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000451785#QSO_RS04735
QSO_RS04735 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000451885#QU5_RS04790
QU5_RS04790 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000530295#BN174_RS04965
BN174_RS04965 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000531255#BN173_RS04920
BN173_RS04920 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000531785#BN176_RS05160
BN176_RS05160 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_000826625#BN2378_RS13505
BN2378_RS13505 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_001484885#CD26A54R_RS04865
CD26A54R_RS04865 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_001484895#CD26A54S_RS04945
CD26A54S_RS04945 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_001857645#HMPREF3082_RS13040
HMPREF3082_RS13040 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_001971835#BER28_RS05245
BER28_RS05245 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_001972015#BER29_RS05190
BER29_RS05190 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002301945#BGU80_RS14245
BGU80_RS14245 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002302755#BGV00_RS10165
BGV00_RS10165 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002302765#BGV01_RS16500
BGV01_RS16500 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002303165#BGV24_RS12650
BGV24_RS12650 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002335485#NCKUH21_RS04775
NCKUH21_RS04775 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002812585#CWR57_RS04555
CWR57_RS04555 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002945415#C3W74_RS05230
C3W74_RS05230 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002945515#C3L34_RS05215
C3L34_RS05215 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002945665#C3347_RS05235
C3347_RS05235 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002945755#C3348_RS05235
C3348_RS05235 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002945855#C3350_RS05245
C3350_RS05245 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002945945#C3349_RS05235
C3349_RS05235 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002946035#C3351_RS05240
C3351_RS05240 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002946135#C3352_RS05245
C3352_RS05245 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002946195#C3353_RS05235
C3353_RS05235 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_002954285#AMR92_RS15450
AMR92_RS15450 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003313545#CDIF27638_RS05225
CDIF27638_RS05225 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003313585#CDIF27640_RS05215
CDIF27640_RS05215 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003482035#CDIF28196_RS05215
CDIF28196_RS05215 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003597795#DA426_RS14690
DA426_RS14690 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003597815#DA430_RS05220
DA430_RS05220 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003597835#DA432_RS05175
DA432_RS05175 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003597895#DA422_RS05235
DA422_RS05235 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003597915#DA436_RS05170
DA436_RS05170 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003625415#C0215_RS14930
C0215_RS14930 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003625425#C0983_RS14645
C0983_RS14645 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9
GCF_003625435#C0984_RS14565
C0984_RS14565 · HK · Classic
RefSeq: WP_009888772.1
UniProt: A0A0H3N1C9

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 413 · GCF_000451785
AssemblyASM45178v2 · Contighaploid
Genome composition4 102 663 bp · 28,5% GCClostridioides difficile P31
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key