Gene detail

QSM_RS15685

Histidine kinase, CheA

Clostridioides difficile P30 · GCF_000451765

ClassHKTypeCheALength700 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000451765#QSM_RS15685Stable P2CS identifier used across views.
GenomeGCF_000451765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0769046Run 6 · 572 sequences · id 100% · cov 80%
External referencesWP_021378385.1 · A0AAN5VNC7 · MIST4 QSM_RS15685RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length700 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage441 / 700 aa (63.0%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa700 aa
Hpt: 3-106 aa (104 aa)1H-kinase_dim: 312-373 aa (62 aa)2HATPase_c: 420-559 aa (140 aa)3CheW: 564-698 aa (135 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
3-106 aa · 104 aa · 14.9% of protein
Raw tokenHpt:3:0.00000000000000959:106:104:84
2 H-kinase_dim#2
312-373 aa · 62 aa · 8.9% of protein
Raw tokenH-kinase_dim:312:0.00000000000000442:373:67:67
3 HATPase_c#3
420-559 aa · 140 aa · 20.0% of protein
Raw tokenHATPase_c:420:1.64e-17:559:140:109
4 CheW#4
564-698 aa · 135 aa · 19.3% of protein
Raw tokenCheW:564:1.87e-22:698:136:138
  • Raw architecture: Hpt:3:0.00000000000000959:106:104:84#H-kinase_dim:312:0.00000000000000442:373:67:67#HATPase_c:420:1.64e-17:559:140:109#CheW:564:1.87e-22:698:136:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000451765::NZ_AVME01000011.1::G00012
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span187827-189929Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQSM_0519RefSeq proteinWP_021378385.1
Context group IDGCF_000451765::NZ_AVME01000011.1::G00012
Context members
QSM_RS15685
Partner locus tags
QSM_RS15685
Partner old locus tags
QSM_0519
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021378385.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN5VNC7Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN5VNC7_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQSM_RS15685Primary locus identifier stored in the genes table.
Old locus tagQSM_0519Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVME01000011.1Sequence record reported by the local genomic context database.
Genomic interval187 827-189 929 nt2 103 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span187 827-189 929 ntGCF_000451765::NZ_AVME01000011.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000451765::NZ_AVME01000011.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVME01000011.1All displayed genes belong to this local TCS context.
Neighborhood span187 827-189 929 nt2 103 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
187 827 nt189 929 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

QSM_RS15685GCF_000451765#QSM_RS15685
HKCheACurrent focus

187 827-189 929 nt · Forward (+)

Old locus QSM_0519RefSeq WP_021378385.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0769046Run 6 · HK · 572 sequences
Representative sequenceGCF_000448745#QC1_RS03730Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0769046

Simplified PFAM architecture for HKOC_0769046

PFAM domain coverage: 513 / 700 aa (73.3%)

1 aa700 aa
Hpt: 3-104 aaHptP2: 164-240 aaP2H-kinase_dim: 312-373 aaH-kinase_dimHATPase_c: 422-559 aaHATPase_cCheW: 565-698 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[3-104] | P2[164-240] | H-kinase_dim[312-373] | HATPase_c[422-559] | CheW[565-698]
  • Domain count: 5
  • Matched identifier: HKOC_0769046
  • Positioned domains: Hpt 3-104 ; P2 164-240 ; H-kinase_dim 312-373 ; HATPase_c 422-559 ; CheW 565-698
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS03730

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 572 total members. Page 1 / 12.

GCF_000448745#QC1_RS03730 (representative)
QC1_RS03730 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000448765#QC5_RS02455
QC5_RS02455 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000448805#QKI_RS03110
QKI_RS03110 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000448925#QC7_RS02935
QC7_RS02935 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000449125#QCQ_RS03245
QCQ_RS03245 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000449205#QMQ_RS02790
QMQ_RS02790 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000449225#QCY_RS03015
QCY_RS03015 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000449245#QEA_RS02975
QEA_RS02975 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000449365#QEQ_RS02960
QEQ_RS02960 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000449705#QGM_RS02445
QGM_RS02445 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000449805#QGY_RS02095
QGY_RS02095 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000449825#QI3_RS02755
QI3_RS02755 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000449925#QIE_RS02855
QIE_RS02855 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000449965#QII_RS02585
QII_RS02585 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000450045#QIS_RS03390
QIS_RS03390 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000450425#QKW_RS02945
QKW_RS02945 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000450445#QKY_RS02495
QKY_RS02495 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000450505#QM5_RS02995
QM5_RS02995 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000450525#QM7_RS02775
QM7_RS02775 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000450585#QMC_RS02650
QMC_RS02650 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000450645#QSA_RS03540
QSA_RS03540 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000450705#QMW_RS03250
QMW_RS03250 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000450845#QOI_RS02520
QOI_RS02520 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000450905#QQI_RS02475
QQI_RS02475 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000451145#QQ1_RS02365
QQ1_RS02365 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000451205#QE5_RS02965
QE5_RS02965 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000451285#QEC_RS02605
QEC_RS02605 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000451365#QOO_RS03915
QOO_RS03915 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000451565#QQO_RS02780
QQO_RS02780 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000451765#QSM_RS15685
QSM_RS15685 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000451865#QU3_RS03045
QU3_RS03045 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000452045#QUM_RS03095
QUM_RS03095 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000452105#QUW_RS02915
QUW_RS02915 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000452205#QW7_RS02960
QW7_RS02960 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000452265#C673_RS02395
C673_RS02395 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000452285#C674_RS02395
C674_RS02395 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000452305#C675_RS02515
C675_RS02515 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000452325#C676_RS03000
C676_RS03000 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000452425#QE3_RS03640
QE3_RS03640 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000473565#QIQ_RS02645
QIQ_RS02645 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000473585#QSS_RS02820
QSS_RS02820 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000473605#QSW_RS02805
QSW_RS02805 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000473665#QUO_RS02945
QUO_RS02945 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000530325#BN178_RS04440
BN178_RS04440 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000530415#BN179_RS02750
BN179_RS02750 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000530475#BN180_RS02440
BN180_RS02440 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000530895#BN181_RS02755
BN181_RS02755 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000531315#BN177_RS05190
BN177_RS05190 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000586575#Y779_RS0102530
Y779_RS0102530 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7
GCF_000821005#TY67_RS08845
TY67_RS08845 · HK · CheA
RefSeq: WP_021378385.1
UniProt: A0AAN5VNC7

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 412 · GCF_000451765
AssemblyASM45176v1 · Contighaploid
Genome composition4 181 432 bp · 28,5% GCClostridioides difficile P30
Signal transduction countsGenes 107 · HK 52 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key