Gene detail

QQW_RS02585

Histidine kinase, Classic

Clostridioides difficile P8 · GCF_000451585

ClassHKTypeClassicLength407 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000451585#QQW_RS02585Stable P2CS identifier used across views.
GenomeGCF_000451585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2380014Run 6 · 75 sequences · id 100% · cov 80%
External referencesWP_330363505.1 · MIST4 QQW_RS02585RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length407 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 407 aa (61.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QQW_RS02585
Domain-by-domain annotation3 items
1 HAMP#1
94-171 aa · 78 aa · 19.2% of protein
Raw tokenHAMP:94:0.00000000532:171:78:69
2 HisKA#2
183-248 aa · 66 aa · 16.2% of protein
Raw tokenHisKA:183:0.00000000333:248:66:64
3 HATPase_c#3
298-404 aa · 107 aa · 26.3% of protein
Raw tokenHATPase_c:298:4.46e-26:404:107:109
  • Raw architecture: HAMP:94:0.00000000532:171:78:69#HisKA:183:0.00000000333:248:66:64#HATPase_c:298:4.46e-26:404:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000451585::NZ_AVLR01000028.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span40249-42384Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQQW_0518RefSeq proteinWP_330363505.1
Context group IDGCF_000451585::NZ_AVLR01000028.1::G00005
Context members
QQW_RS02580QQW_RS02585
Partner locus tags
QQW_RS02580QQW_RS02585
Partner old locus tags
QQW_0517QQW_0518
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330363505.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQQW_RS02585Primary locus identifier stored in the genes table.
Old locus tagQQW_0518Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVLR01000028.1Sequence record reported by the local genomic context database.
Genomic interval41 161-42 384 nt1 224 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span40 249-42 384 ntGCF_000451585::NZ_AVLR01000028.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000451585::NZ_AVLR01000028.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVLR01000028.1All displayed genes belong to this local TCS context.
Neighborhood span40 249-42 384 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
40 249 nt42 384 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QQW_RS02580GCF_000451585#QQW_RS02580
RROmpR

40 249-40 941 nt · Forward (+)

Old locus QQW_0517RefSeq WP_009901954.1
QQW_RS02585GCF_000451585#QQW_RS02585
HKClassicCurrent focus

41 161-42 384 nt · Forward (+)

Old locus QQW_0518RefSeq WP_330363505.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2380014Run 6 · HK · 75 sequences
Representative sequenceGCF_000155025#UAB_RS0203575Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2380014

Simplified PFAM architecture for HKOC_2380014

PFAM domain coverage: 223 / 407 aa (54.8%)

1 aa407 aa
HAMP: 121-171 aaHAMPHisKA: 184-248 aaHisKAHATPase_c: 298-404 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[121-171] | HisKA[184-248] | HATPase_c[298-404]
  • Domain count: 3
  • Matched identifier: HKOC_2380014
  • Positioned domains: HAMP 121-171 ; HisKA 184-248 ; HATPase_c 298-404
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0203575

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 399 · GCF_000451585
AssemblyASM45158v2 · Contighaploid
Genome composition4 292 666 bp · 28,0% GCClostridioides difficile P8
Signal transduction countsGenes 99 · HK 47 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key