Gene detail

QQC_RS09745

Histidine kinase, Classic

Clostridioides difficile Y358 · GCF_000451525

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000451525#QQC_RS09745Stable P2CS identifier used across views.
GenomeGCF_000451525Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2827743Run 6 · 91 sequences · id 100% · cov 80%
External referencesWP_011861402.1 · Q187S1 · MIST4 QQC_RS09745RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QQC_RS09745
Domain-by-domain annotation2 items
1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw tokenHisKA:124:0.000000283:189:66:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:5.28e-24:341:101:109
  • Raw architecture: HisKA:124:0.000000283:189:66:64#HATPase_c:241:5.28e-24:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000451525::NZ_AVLH01000045.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span78898-80605Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQQC_1887RefSeq proteinWP_011861402.1
Context group IDGCF_000451525::NZ_AVLH01000045.1::G00037
Context members
QQC_RS09740QQC_RS09745
Partner locus tags
QQC_RS09740QQC_RS09745
Partner old locus tags
QQC_1886QQC_1887
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_011861402.1Primary protein accession used for annex mappings.
UniProt accessionQ187S1Primary UniProt accession resolved in the annex database.
UniProt IDQ187S1_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQQC_RS09745Primary locus identifier stored in the genes table.
Old locus tagQQC_1887Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVLH01000045.1Sequence record reported by the local genomic context database.
Genomic interval79 574-80 605 nt1 032 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span78 898-80 605 ntGCF_000451525::NZ_AVLH01000045.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000451525::NZ_AVLH01000045.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVLH01000045.1All displayed genes belong to this local TCS context.
Neighborhood span78 898-80 605 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
78 898 nt80 605 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QQC_RS09740GCF_000451525#QQC_RS09740
RROmpR

78 898-79 584 nt · Forward (+)

Old locus QQC_1886RefSeq WP_011861401.1
QQC_RS09745GCF_000451525#QQC_RS09745
HKClassicCurrent focus

79 574-80 605 nt · Forward (+)

Old locus QQC_1887RefSeq WP_011861402.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2827743Run 6 · HK · 91 sequences
Representative sequenceGCF_000009205#CD630_RS10615Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2827743

Simplified PFAM architecture for HKOC_2827743

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2827743
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS10615

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 389 · GCF_000451525
AssemblyASM45152v2 · Contighaploid
Genome composition4 152 679 bp · 29,0% GCClostridioides difficile Y358
Signal transduction countsGenes 101 · HK 47 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key