Gene detail

QEC_RS07090

Histidine kinase, Classic

Clostridioides difficile CD111 · GCF_000451285

ClassHKTypeClassicLength417 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000451285#QEC_RS07090Stable P2CS identifier used across views.
GenomeGCF_000451285Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2293545Run 6 · 574 sequences · id 100% · cov 80%
External referencesWP_003438652.1 · MIST4 QEC_RS07090RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length417 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 417 aa (40.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QEC_RS07090
Domain-by-domain annotation2 items
1 HisKA#1
199-258 aa · 60 aa · 14.4% of protein
Raw tokenHisKA:199:0.00000000124:258:60:64
2 HATPase_c#2
304-410 aa · 107 aa · 25.7% of protein
Raw tokenHATPase_c:304:2.14e-21:410:107:109
  • Raw architecture: HisKA:199:0.00000000124:258:60:64#HATPase_c:304:2.14e-21:410:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000451285::NZ_AVHM01000088.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span40289-42245Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQEC_1431RefSeq proteinWP_003438652.1
Context group IDGCF_000451285::NZ_AVHM01000088.1::G00019
Context members
QEC_RS07085QEC_RS07090
Partner locus tags
QEC_RS07085QEC_RS07090
Partner old locus tags
QEC_1430QEC_1431
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_003438652.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQEC_RS07090Primary locus identifier stored in the genes table.
Old locus tagQEC_1431Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHM01000088.1Sequence record reported by the local genomic context database.
Genomic interval40 992-42 245 nt1 254 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span40 289-42 245 ntGCF_000451285::NZ_AVHM01000088.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000451285::NZ_AVHM01000088.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHM01000088.1All displayed genes belong to this local TCS context.
Neighborhood span40 289-42 245 nt1 957 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
40 289 nt42 245 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QEC_RS07085GCF_000451285#QEC_RS07085
RROmpR

40 289-41 014 nt · Forward (+)

Old locus QEC_1430RefSeq WP_003438649.1
QEC_RS07090GCF_000451285#QEC_RS07090
HKClassicCurrent focus

40 992-42 245 nt · Forward (+)

Old locus QEC_1431RefSeq WP_003438652.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2293545Run 6 · HK · 574 sequences
Representative sequenceGCF_000235905#HMPREF9945_RS05765Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2293545

Simplified PFAM architecture for HKOC_2293545

PFAM domain coverage: 169 / 417 aa (40.5%)

1 aa417 aa
HisKA: 196-258 aaHisKAHATPase_c: 305-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[196-258] | HATPase_c[305-410]
  • Domain count: 2
  • Matched identifier: HKOC_2293545
  • Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000235905#HMPREF9945_RS05765

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 282 · GCF_000451285
AssemblyASM45128v2 · Contighaploid
Genome composition4 047 257 bp · 28,5% GCClostridioides difficile CD111
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key