Gene detail

QEC_RS03140

Histidine kinase, Classic

Clostridioides difficile CD111 · GCF_000451285

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000451285#QEC_RS03140Stable P2CS identifier used across views.
GenomeGCF_000451285Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2882093Run 6 · 370 sequences · id 100% · cov 80%
External referencesWP_021368207.1 · A0A9X8WPU8 · MIST4 QEC_RS03140RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 305 aa (57.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QEC_RS03140
Domain-by-domain annotation2 items
1 HisKA#1
85-154 aa · 70 aa · 23.0% of protein
Raw tokenHisKA:85:0.0000000000009:154:70:64
2 HATPase_c#2
201-304 aa · 104 aa · 34.1% of protein
Raw tokenHATPase_c:201:1.26e-27:304:106:109
  • Raw architecture: HisKA:85:0.0000000000009:154:70:64#HATPase_c:201:1.26e-27:304:106:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000451285::NZ_AVHM01000049.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span9412-11018Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQEC_0615RefSeq proteinWP_021368207.1
Context group IDGCF_000451285::NZ_AVHM01000049.1::G00011
Context members
QEC_RS03135QEC_RS03140
Partner locus tags
QEC_RS03135QEC_RS03140
Partner old locus tags
QEC_0614QEC_0615
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021368207.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8WPU8Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8WPU8_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQEC_RS03140Primary locus identifier stored in the genes table.
Old locus tagQEC_0615Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHM01000049.1Sequence record reported by the local genomic context database.
Genomic interval10 101-11 018 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span9 412-11 018 ntGCF_000451285::NZ_AVHM01000049.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000451285::NZ_AVHM01000049.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHM01000049.1All displayed genes belong to this local TCS context.
Neighborhood span9 412-11 018 nt1 607 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 412 nt11 018 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QEC_RS03135GCF_000451285#QEC_RS03135
RROmpR

9 412-10 101 nt · Forward (+)

Old locus QEC_0614RefSeq WP_021358912.1
QEC_RS03140GCF_000451285#QEC_RS03140
HKClassicCurrent focus

10 101-11 018 nt · Forward (+)

Old locus QEC_0615RefSeq WP_021368207.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2882093Run 6 · HK · 370 sequences
Representative sequenceGCF_000448805#QKI_RS03630Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2882093

Simplified PFAM architecture for HKOC_2882093

PFAM domain coverage: 171 / 305 aa (56.1%)

1 aa305 aa
HisKA: 88-154 aaHisKAHATPase_c: 201-304 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[88-154] | HATPase_c[201-304]
  • Domain count: 2
  • Matched identifier: HKOC_2882093
  • Positioned domains: HisKA 88-154 ; HATPase_c 201-304
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448805#QKI_RS03630

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 282 · GCF_000451285
AssemblyASM45128v2 · Contighaploid
Genome composition4 047 257 bp · 28,5% GCClostridioides difficile CD111
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key