Gene detail

QQQ_RS05005

Histidine kinase, Classic

Clostridioides difficile P5 · GCF_000450965

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450965#QQQ_RS05005Stable P2CS identifier used across views.
GenomeGCF_000450965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1504291Run 6 · 907 sequences · id 100% · cov 80%
External referencesWP_003437034.1 · A0A031WG74 · MIST4 QQQ_RS05005RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 212-279 aa (68 aa)1HisKA: 289-347 aa (59 aa)2HATPase_c: 395-495 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw tokenHAMP:212:0.00000634:279:68:69
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw tokenHisKA:289:4.11e-17:347:59:64
3 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw tokenHATPase_c:395:2.8e-27:495:106:109
  • Raw architecture: HAMP:212:0.00000634:279:68:69#HisKA:289:4.11e-17:347:59:64#HATPase_c:395:2.8e-27:495:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450965::NZ_AVLO01000056.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18337-20530Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQQQ_0985RefSeq proteinWP_003437034.1
Context group IDGCF_000450965::NZ_AVLO01000056.1::G00014
Context members
QQQ_RS05000QQQ_RS05005
Partner locus tags
QQQ_RS05000QQQ_RS05005
Partner old locus tags
QQQ_0984QQQ_0985
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003437034.1Primary protein accession used for annex mappings.
UniProt accessionA0A031WG74Primary UniProt accession resolved in the annex database.
UniProt IDA0A031WG74_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQQQ_RS05005Primary locus identifier stored in the genes table.
Old locus tagQQQ_0985Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVLO01000056.1Sequence record reported by the local genomic context database.
Genomic interval19 043-20 530 nt1 488 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span18 337-20 530 ntGCF_000450965::NZ_AVLO01000056.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450965::NZ_AVLO01000056.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVLO01000056.1All displayed genes belong to this local TCS context.
Neighborhood span18 337-20 530 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 337 nt20 530 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QQQ_RS05000GCF_000450965#QQQ_RS05000
RROmpR

18 337-19 041 nt · Forward (+)

Old locus QQQ_0984RefSeq WP_003437036.1
QQQ_RS05005GCF_000450965#QQQ_RS05005
HKClassicCurrent focus

19 043-20 530 nt · Forward (+)

Old locus QQQ_0985RefSeq WP_003437034.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504291Run 6 · HK · 907 sequences
Representative sequenceGCF_000155025#UAB_RS0205810Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504291

Simplified PFAM architecture for HKOC_1504291

PFAM domain coverage: 161 / 495 aa (32.5%)

1 aa495 aa
HisKA: 287-347 aaHisKAHATPase_c: 395-494 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[287-347] | HATPase_c[395-494]
  • Domain count: 2
  • Matched identifier: HKOC_1504291
  • Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0205810

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 396 · GCF_000450965
AssemblyASM45096v2 · Contighaploid
Genome composition4 048 946 bp · 28,5% GCClostridioides difficile P5
Signal transduction countsGenes 92 · HK 45 · RR 47CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key