Gene detail

QQQ_RS02440

Histidine kinase, Classic

Clostridioides difficile P5 · GCF_000450965

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450965#QQQ_RS02440Stable P2CS identifier used across views.
GenomeGCF_000450965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1674086Run 6 · 679 sequences · id 100% · cov 80%
External referencesWP_003434751.1 · Q188S3 · MIST4 QQQ_RS02440RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QQQ_RS02440
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000139:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000206:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:2.74e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000139:238:78:69#HisKA:250:0.00000000206:315:66:64#HATPase_c:365:2.74e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450965::NZ_AVLO01000029.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span41481-43616Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQQQ_0461RefSeq proteinWP_003434751.1
Context group IDGCF_000450965::NZ_AVLO01000029.1::G00003
Context members
QQQ_RS02435QQQ_RS02440
Partner locus tags
QQQ_RS02435QQQ_RS02440
Partner old locus tags
QQQ_0460QQQ_0461
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003434751.1Primary protein accession used for annex mappings.
UniProt accessionQ188S3Primary UniProt accession resolved in the annex database.
UniProt IDQ188S3_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQQQ_RS02440Primary locus identifier stored in the genes table.
Old locus tagQQQ_0461Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVLO01000029.1Sequence record reported by the local genomic context database.
Genomic interval42 192-43 616 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span41 481-43 616 ntGCF_000450965::NZ_AVLO01000029.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450965::NZ_AVLO01000029.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVLO01000029.1All displayed genes belong to this local TCS context.
Neighborhood span41 481-43 616 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
41 481 nt43 616 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QQQ_RS02435GCF_000450965#QQQ_RS02435
RROmpR

41 481-42 173 nt · Forward (+)

Old locus QQQ_0460RefSeq WP_003434748.1
QQQ_RS02440GCF_000450965#QQQ_RS02440
HKClassicCurrent focus

42 192-43 616 nt · Forward (+)

Old locus QQQ_0461RefSeq WP_003434751.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674086Run 6 · HK · 679 sequences
Representative sequenceGCF_000009205#CD630_RS02960Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674086

Simplified PFAM architecture for HKOC_1674086

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1674086
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS02960

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 396 · GCF_000450965
AssemblyASM45096v2 · Contighaploid
Genome composition4 048 946 bp · 28,5% GCClostridioides difficile P5
Signal transduction countsGenes 92 · HK 45 · RR 47CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key