Gene detail

QOI_RS02520

Histidine kinase, CheA

Clostridioides difficile Y21 · GCF_000450845

ClassHKTypeCheALength700 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000450845#QOI_RS02520Stable P2CS identifier used across views.
GenomeGCF_000450845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0769046Run 6 · 572 sequences · id 100% · cov 80%
External referencesWP_021378385.1 · A0AAN5VNC7 · MIST4 QOI_RS02520RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length700 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage441 / 700 aa (63.0%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa700 aa
Hpt: 3-106 aa (104 aa)1H-kinase_dim: 312-373 aa (62 aa)2HATPase_c: 420-559 aa (140 aa)3CheW: 564-698 aa (135 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
3-106 aa · 104 aa · 14.9% of protein
Raw tokenHpt:3:0.00000000000000959:106:104:84
2 H-kinase_dim#2
312-373 aa · 62 aa · 8.9% of protein
Raw tokenH-kinase_dim:312:0.00000000000000442:373:67:67
3 HATPase_c#3
420-559 aa · 140 aa · 20.0% of protein
Raw tokenHATPase_c:420:1.64e-17:559:140:109
4 CheW#4
564-698 aa · 135 aa · 19.3% of protein
Raw tokenCheW:564:1.87e-22:698:136:138
  • Raw architecture: Hpt:3:0.00000000000000959:106:104:84#H-kinase_dim:312:0.00000000000000442:373:67:67#HATPase_c:420:1.64e-17:559:140:109#CheW:564:1.87e-22:698:136:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000450845::NZ_AVKS01000024.1::G00009
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span31962-34064Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQOI_0507RefSeq proteinWP_021378385.1
Context group IDGCF_000450845::NZ_AVKS01000024.1::G00009
Context members
QOI_RS02520
Partner locus tags
QOI_RS02520
Partner old locus tags
QOI_0507
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021378385.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN5VNC7Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN5VNC7_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQOI_RS02520Primary locus identifier stored in the genes table.
Old locus tagQOI_0507Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVKS01000024.1Sequence record reported by the local genomic context database.
Genomic interval31 962-34 064 nt2 103 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span31 962-34 064 ntGCF_000450845::NZ_AVKS01000024.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450845::NZ_AVKS01000024.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVKS01000024.1All displayed genes belong to this local TCS context.
Neighborhood span31 962-34 064 nt2 103 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
31 962 nt34 064 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

QOI_RS02520GCF_000450845#QOI_RS02520
HKCheACurrent focus

31 962-34 064 nt · Forward (+)

Old locus QOI_0507RefSeq WP_021378385.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0769046Run 6 · HK · 572 sequences
Representative sequenceGCF_000448745#QC1_RS03730Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0769046

Simplified PFAM architecture for HKOC_0769046

PFAM domain coverage: 513 / 700 aa (73.3%)

1 aa700 aa
Hpt: 3-104 aaHptP2: 164-240 aaP2H-kinase_dim: 312-373 aaH-kinase_dimHATPase_c: 422-559 aaHATPase_cCheW: 565-698 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[3-104] | P2[164-240] | H-kinase_dim[312-373] | HATPase_c[422-559] | CheW[565-698]
  • Domain count: 5
  • Matched identifier: HKOC_0769046
  • Positioned domains: Hpt 3-104 ; P2 164-240 ; H-kinase_dim 312-373 ; HATPase_c 422-559 ; CheW 565-698
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS03730

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 374 · GCF_000450845
AssemblyASM45084v2 · Contighaploid
Genome composition4 079 115 bp · 28,5% GCClostridioides difficile Y21
Signal transduction countsGenes 96 · HK 46 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key