Gene detail

QO3_RS03630

Histidine kinase, Classic

Clostridioides difficile F249 · GCF_000450745

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450745#QO3_RS03630Stable P2CS identifier used across views.
GenomeGCF_000450745Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2882092Run 6 · 169 sequences · id 100% · cov 80%
External referencesWP_021366243.1 · A0A069A5W9 · MIST4 QO3_RS03630RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 305 aa (57.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QO3_RS03630
Domain-by-domain annotation2 items
1 HisKA#1
85-154 aa · 70 aa · 23.0% of protein
Raw tokenHisKA:85:0.00000000000163:154:70:64
2 HATPase_c#2
201-304 aa · 104 aa · 34.1% of protein
Raw tokenHATPase_c:201:5.74e-28:304:106:109
  • Raw architecture: HisKA:85:0.00000000000163:154:70:64#HATPase_c:201:5.74e-28:304:106:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450745::NZ_AVKN01000027.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span14952-16558Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQO3_0690RefSeq proteinWP_021366243.1
Context group IDGCF_000450745::NZ_AVKN01000027.1::G00012
Context members
QO3_RS03625QO3_RS03630
Partner locus tags
QO3_RS03625QO3_RS03630
Partner old locus tags
QO3_0689QO3_0690
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366243.1Primary protein accession used for annex mappings.
UniProt accessionA0A069A5W9Primary UniProt accession resolved in the annex database.
UniProt IDA0A069A5W9_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQO3_RS03630Primary locus identifier stored in the genes table.
Old locus tagQO3_0690Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVKN01000027.1Sequence record reported by the local genomic context database.
Genomic interval15 641-16 558 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span14 952-16 558 ntGCF_000450745::NZ_AVKN01000027.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450745::NZ_AVKN01000027.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVKN01000027.1All displayed genes belong to this local TCS context.
Neighborhood span14 952-16 558 nt1 607 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
14 952 nt16 558 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QO3_RS03625GCF_000450745#QO3_RS03625
RROmpR

14 952-15 641 nt · Forward (+)

Old locus QO3_0689RefSeq WP_016729263.1
QO3_RS03630GCF_000450745#QO3_RS03630
HKClassicCurrent focus

15 641-16 558 nt · Forward (+)

Old locus QO3_0690RefSeq WP_021366243.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2882092Run 6 · HK · 169 sequences
Representative sequenceGCF_000448765#QC5_RS03005Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2882092

Simplified PFAM architecture for HKOC_2882092

PFAM domain coverage: 171 / 305 aa (56.1%)

1 aa305 aa
HisKA: 88-154 aaHisKAHATPase_c: 201-304 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[88-154] | HATPase_c[201-304]
  • Domain count: 2
  • Matched identifier: HKOC_2882092
  • Positioned domains: HisKA 88-154 ; HATPase_c 201-304
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS03005

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 169 total members. Page 1 / 4.

GCF_000448765#QC5_RS03005 (representative)
QC5_RS03005 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000449005#QCE_RS03025
QCE_RS03025 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000449325#QEM_RS02830
QEM_RS02830 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000449405#QEU_RS03025
QEU_RS03025 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000449445#QEY_RS03220
QEY_RS03220 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000449565#QMI_RS03620
QMI_RS03620 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000449625#QMM_RS03355
QMM_RS03355 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000449705#QGM_RS03125
QGM_RS03125 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000449905#QIC_RS03475
QIC_RS03475 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000450185#QK7_RS03865
QK7_RS03865 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000450205#QK9_RS03660
QK9_RS03660 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000450325#QKM_RS02685
QKM_RS02685 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000450405#QKU_RS03665
QKU_RS03665 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000450445#QKY_RS03040
QKY_RS03040 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000450685#QMU_RS02975
QMU_RS02975 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000450745#QO3_RS03630
QO3_RS03630 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000450945#QQM_RS03295
QQM_RS03295 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000451425#QOY_RS03265
QOY_RS03265 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000451525#QQC_RS03350
QQC_RS03350 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000451665#QS3_RS03415
QS3_RS03415 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000451705#QS7_RS15430
QS7_RS15430 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000451725#QS9_RS03160
QS9_RS03160 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000451905#QU7_RS03195
QU7_RS03195 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000451945#QUA_RS03230
QUA_RS03230 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000452265#C673_RS02950
C673_RS02950 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000452285#C674_RS02945
C674_RS02945 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000452305#C675_RS03060
C675_RS03060 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000452325#C676_RS03540
C676_RS03540 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000473605#QSW_RS03355
QSW_RS03355 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000473645#QUG_RS03455
QUG_RS03455 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000473685#QUQ_RS03540
QUQ_RS03540 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000586575#Y779_RS0103065
Y779_RS0103065 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_000939295#BN1097_RS03510
BN1097_RS03510 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_001192735#AWU81_RS01205
AWU81_RS01205 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_001263655#AWU80_RS18345
AWU80_RS18345 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_001263675#AWU78_RS16110
AWU78_RS16110 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_001263695#AWU79_RS17265
AWU79_RS17265 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_002301075#BGU05_RS15100
BGU05_RS15100 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_002301105#BGU08_RS03075
BGU08_RS03075 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_002301505#BGU27_RS10820
BGU27_RS10820 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_002301895#BGU49_RS14980
BGU49_RS14980 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_002301975#BGU82_RS17295
BGU82_RS17295 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_002302795#BGV04_RS14715
BGV04_RS14715 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_002302885#BGV09_RS05690
BGV09_RS05690 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_002303125#BGV22_RS12370
BGV22_RS12370 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_003044135#DA089_RS14030
DA089_RS14030 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_003044155#C5H93_RS14810
C5H93_RS14810 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_003481905#CDIF29688_RS03845
CDIF29688_RS03845 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_003490105#CDIF28668_RS03605
CDIF28668_RS03605 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9
GCF_003597855#DA434_RS03665
DA434_RS03665 · HK · Classic
RefSeq: WP_021366243.1
UniProt: A0A069A5W9

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 366 · GCF_000450745
AssemblyASM45074v2 · Contighaploid
Genome composition4 206 521 bp · 28,5% GCClostridioides difficile F249
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key