Gene detail

QMU_RS02330

Histidine kinase, Classic

Clostridioides difficile DA00310 · GCF_000450685

ClassHKTypeClassicLength535 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450685#QMU_RS02330Stable P2CS identifier used across views.
GenomeGCF_000450685Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1338482Run 6 · 2212 sequences · id 100% · cov 80%
External referencesWP_003439079.1 · A0A0H3MZ77 · MIST4 QMU_RS02330RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length535 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage178 / 535 aa (33.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QMU_RS02330
Domain-by-domain annotation2 items
1 HisKA#1
304-371 aa · 68 aa · 12.7% of protein
Raw tokenHisKA:304:0.00000000000013:371:68:64
2 HATPase_c#2
416-525 aa · 110 aa · 20.6% of protein
Raw tokenHATPase_c:416:2.53e-31:525:110:109
  • Raw architecture: HisKA:304:0.00000000000013:371:68:64#HATPase_c:416:2.53e-31:525:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450685::NZ_AVKK01000061.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3213-5515Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQMU_0471RefSeq proteinWP_003439079.1
Context group IDGCF_000450685::NZ_AVKK01000061.1::G00007
Context members
QMU_RS02330QMU_RS02335
Partner locus tags
QMU_RS02330QMU_RS02335
Partner old locus tags
QMU_0471QMU_0472
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003439079.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MZ77Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MZ77_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQMU_RS02330Primary locus identifier stored in the genes table.
Old locus tagQMU_0471Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVKK01000061.1Sequence record reported by the local genomic context database.
Genomic interval3 213-4 820 nt1 608 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 213-5 515 ntGCF_000450685::NZ_AVKK01000061.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450685::NZ_AVKK01000061.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVKK01000061.1All displayed genes belong to this local TCS context.
Neighborhood span3 213-5 515 nt2 303 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 213 nt5 515 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QMU_RS02330GCF_000450685#QMU_RS02330
HKClassicCurrent focus

3 213-4 820 nt · Forward (+)

Old locus QMU_0471RefSeq WP_003439079.1
QMU_RS02335GCF_000450685#QMU_RS02335
RROmpR

4 811-5 515 nt · Forward (+)

Old locus QMU_0472RefSeq WP_003439080.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1338482Run 6 · HK · 2212 sequences
Representative sequenceGCF_000003215#QAC_RS0202670Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1338482

Simplified PFAM architecture for HKOC_1338482

PFAM domain coverage: 286 / 535 aa (53.5%)

1 aa535 aa
DUF4118: 32-139 aaDUF4118HisKA: 304-371 aaHisKAHATPase_c: 416-525 aaHATPase_c
DUF4118HisKAHATPase_c
  • Simplified architecture: DUF4118 + HisKA + HATPase_c
  • Raw architecture: DUF4118[32-139] | HisKA[304-371] | HATPase_c[416-525]
  • Domain count: 3
  • Matched identifier: HKOC_1338482
  • Positioned domains: DUF4118 32-139 ; HisKA 304-371 ; HATPase_c 416-525
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0202670

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 362 · GCF_000450685
AssemblyASM45068v2 · Contighaploid
Genome composition3 909 936 bp · 28,5% GCClostridioides difficile DA00310
Signal transduction countsGenes 97 · HK 45 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key