1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw token
HisKA_3:188:3.27e-20:253:67:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QME_RS06630
Histidine kinase, Classic
Clostridioides difficile DA00246 · GCF_000450605
ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450605#QME_RS06630Stable P2CS identifier used across views.
GenomeGCF_000450605Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa387 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw token
HATPase_c:294:0.00000000777:378:104:109- Raw architecture: HisKA_3:188:3.27e-20:253:67:68#HATPase_c:294:0.00000000777:378:104:109
- Domain description: 1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000450605::NZ_AVKC01000029.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span224227-226030Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQME_1217RefSeq proteinWP_021373389.1
Context group ID
GCF_000450605::NZ_AVKC01000029.1::G00019Context members
QME_RS06625QME_RS06630
Partner locus tags
QME_RS06625QME_RS06630
Partner old locus tags
QME_1216QME_1217
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021373389.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQME_RS06630Primary locus identifier stored in the genes table.
Old locus tagQME_1217Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVKC01000029.1Sequence record reported by the local genomic context database.
Genomic interval224 867-226 030 nt1 164 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span224 227-226 030 ntGCF_000450605::NZ_AVKC01000029.1::G00019
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000450605::NZ_AVKC01000029.1::G00019Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVKC01000029.1All displayed genes belong to this local TCS context.
Neighborhood span224 227-226 030 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
224 227 nt226 030 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QME_RS06625GCF_000450605#QME_RS06625
RRNarL
224 227-224 874 nt · Reverse (-)
QME_RS06630GCF_000450605#QME_RS06630
HKClassicCurrent focus
224 867-226 030 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004318545#E0R11_RS17805Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2453446
Simplified PFAM architecture for HKOC_2453446
PFAM domain coverage: 150 / 399 aa (37.6%)
1 aa399 aa
HisKA_3HATPase_c
- Simplified architecture: HisKA_3 + HATPase_c
- Raw architecture: HisKA_3[200-264] | HATPase_c[306-390]
- Domain count: 2
- Matched identifier: HKOC_2453446
- Positioned domains: HisKA_3 200-264 ; HATPase_c 306-390
Cluster members and taxonomy
Representative gene: GCF_004318545#E0R11_RS17805
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 354 · GCF_000450605
AssemblyASM45060v2 · Contighaploid
Genome composition4 093 262 bp · 28,5% GCClostridioides difficile DA00246
Signal transduction countsGenes 103 · HK 48 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key