Gene detail

QMC_RS05995

Histidine kinase, Classic

Clostridioides difficile DA00245 · GCF_000450585

ClassHKTypeClassicLength336 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450585#QMC_RS05995Stable P2CS identifier used across views.
GenomeGCF_000450585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550380Run 6 · 201 sequences · id 100% · cov 80%
External referencesWP_032544822.1 · MIST4 QMC_RS05995RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length336 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 336 aa (44.9%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa336 aa
HisKA_3: 137-202 aa (66 aa)1HATPase_c: 243-327 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
137-202 aa · 66 aa · 19.6% of protein
Raw tokenHisKA_3:137:2.13e-20:202:67:68
2 HATPase_c#2
243-327 aa · 85 aa · 25.3% of protein
Raw tokenHATPase_c:243:0.000000000227:327:104:109
  • Raw architecture: HisKA_3:137:2.13e-20:202:67:68#HATPase_c:243:0.000000000227:327:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450585::NZ_AVKB01000101.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8643-10295Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQMC_1224RefSeq proteinWP_032544822.1
Context group IDGCF_000450585::NZ_AVKB01000101.1::G00018
Context members
QMC_RS05990QMC_RS05995
Partner locus tags
QMC_RS05990QMC_RS05995
Partner old locus tags
QMC_1223QMC_1224
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_032544822.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQMC_RS05995Primary locus identifier stored in the genes table.
Old locus tagQMC_1224Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVKB01000101.1Sequence record reported by the local genomic context database.
Genomic interval9 283-10 295 nt1 013 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span8 643-10 295 ntGCF_000450585::NZ_AVKB01000101.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450585::NZ_AVKB01000101.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVKB01000101.1All displayed genes belong to this local TCS context.
Neighborhood span8 643-10 295 nt1 653 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 643 nt10 295 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QMC_RS05990GCF_000450585#QMC_RS05990
RRNarL

8 643-9 290 nt · Reverse (-)

Old locus QMC_1223RefSeq WP_009896181.1
QMC_RS05995GCF_000450585#QMC_RS05995
HKClassicCurrent focus

9 283-10 295 nt · Reverse (-)

Old locus QMC_1224RefSeq WP_032544822.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550380Run 6 · HK · 201 sequences
Representative sequenceGCF_000448745#QC1_RS06915Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550380

Simplified PFAM architecture for HKOC_2550380

PFAM domain coverage: 150 / 387 aa (38.8%)

1 aa387 aa
HisKA_3: 188-252 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550380
  • Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS06915

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 353 · GCF_000450585
AssemblyASM45058v2 · Contighaploid
Genome composition3 985 935 bp · 28,5% GCClostridioides difficile DA00245
Signal transduction countsGenes 95 · HK 46 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key